Results 91 to 100 of about 1,184,096 (322)

An Interleaving Hybrid Consensus Protocol

, 2019
We introduce Unity Interleave, a new consensus algorithm for public blockchain settings. It is an eventual consistency protocol merging the Proof-of-Work (PoW) and Proof-of-Stake (PoS) into a coherent stochastic process. It builds upon research previously done for the Unity protocol, improving security while maintaining fairness and scalability.
Sun, Yao, Rajasekaran, Aayush
openaire   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

A Distributed Consensus Protocol Based on Neighbor Selection Strategies for Multi-Agent Systems Convergence

IEEE Access, 2019
Multi-agent systems (MASs), which consist of numerous mobile agents, is a promising research area in artificial intelligence that has been profusely applied to Engineering. A consensus problem of discrete time MASs with switching topology is investigated
Guangqiang Xie, Tianxiang Lan, Xianbiao Hu, Yang Li, Chang-Dong Wang, Yuyu Yin   +5 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

A Secure and Scalable IoT Consensus Protocol

, 2022
Beverley A. MacKenzie, Ian Ferguson, Abdul Razaq   +2 more
openalex   +2 more sources

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

SARS-CoV-2 NCBI consensus submission protocol: GenBank v2 [PDF]

, 2020
Ruth Timme, Heather M. Blankenship, Pavitra Roychoudhury, Erin L. Young, Emma Griffiths, Duncan MacCannell, Stacia K. Wyman, Lee S. Katz   +7 more
openalex   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

An improved practical Byzantine fault tolerance algorithm for aggregating node preferences

Scientific Reports
Consensus algorithms play a critical role in maintaining the consistency of blockchain data, directly affecting the system’s security and stability, and are used to determine the binary consensus of whether proposals are correct.
Xu Liu, Junwu Zhu
doaj   +1 more source

Novel Lightweight Consensus Protocol for Reaching Blockchain Consensus in Low Bandwidth Network Environment

, 2023
Minsung Son, Heeyoul Kim
openalex   +1 more source