Results 91 to 100 of about 6,708,642 (339)

Ethical issues in implementation research: a discussion of the problems in achieving informed consent [PDF]

open access: yes, 2008
Background: Improved quality of care is a policy objective of health care systems around the world. Implementation research is the scientific study of methods to promote the systematic uptake of clinical research findings into routine clinical practice ...
A Iversen   +39 more
core   +3 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

The Definition of Trafficking in Adult Persons for Various Forms of Exploitation and the Issue of Consent: A Framework Approach that Respects Peculiarities

open access: yesGroningen Journal of International Law, 2013
The article discusses the problems determined by the interpretation of the definition of trafficking in adult persons contained in Article 3(a) of the UN Trafficking Protocol as including the element of the improper means and vitiated consent.
Silvia Scarpa
doaj   +1 more source

The Prejudicial Effects of 'Reasonable Steps' in Analysis of Mens Rea and Sexual Consent: Two Solutions [PDF]

open access: yes, 2018
This article examines the operation of “reasonable steps” as a statutory standard for analysis of the availability of the defence of belief in consent in sexual assault cases and concludes that application of section 273.2(b) of the Criminal Code, as ...
Vandervort, Lucinda
core  

Health Research Access to Personal Confidential Data in England and Wales: Assessing any gap in public attitude between preferable and acceptable models of consent [PDF]

open access: yes, 2014
England and Wales are moving toward a model of ‘opt out’ for use of personal confidential data in health research. Existing research does not make clear how acceptable this move is to the public.
Taylor, Mark J., Taylor, Natasha
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

The Obligation on an Intervening State to Respect the Host State’s IHL and IHRL Obligations in an Intervention by Invitation: An Analysis of the Saudi Intervention in Yemen

open access: yesGroningen Journal of International Law, 2018
Interventions by invitation of the government have been attracting increasing interest from legal scholars in recent years. This increased interest can be attributed to the increasing frequency at which States, including Saudi Arabia in Yemen, use such ...
Louis Koen, Brooke Hanson
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Imagined, Real and Moral Economies

open access: yesCulture Unbound: Journal of Current Cultural Research, 2014
This article explores three different inflections of the idea of economy: imagined, real and moral. Each offers a distinctive way of thinking about economies and each raises the possibility of providing critical purchase on the formations of ’actually ...
John Clarke
doaj   +1 more source

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