Results 141 to 150 of about 6,708,642 (339)
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Circular 02/12 : college involvement in companies : consent to participate in, subscribe for or otherwise acquire shares, or securities of, companies providing education funded wholly or partly by the Council [PDF]
, 2002 "This Circular confirms that Further Education Corporations (Colleges) have a power to participate in, to subscribe for or otherwise acquire shares in, or securities of, companies.
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Voluntary Contributions by Consent or Dissent [PDF]
We study games where voluntary contributions can be adjusted until a steady state is found. In consent games contributions start at zero and can be increased by consent, and in dissent games contributions start high and can be decreased by dissent ...
Bolle, Friedel +2 more
core +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
The Journal of Consent-Based PerformanceThrough the adaptation of trauma-informed pedagogy, intimacy and consent-based practices, and the use of sself-care cues or safe words, this note recounts one lecturer's integration of Consent-Forward practice into their teaching in Higher Education in ...
Joshua Richardson
doaj +1 more source
Normative Consent Is Not Consent [PDF]
Cambridge Quarterly of Healthcare Ethics, 2012 openaire +3 more sources
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source