Results 261 to 270 of about 6,708,642 (339)
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin +6 more
wiley +1 more source
Comment on "Improving consenting practice in trauma and orthopaedics: A single centre original mixed methods study". [PDF]
Batra A, Kokiwar P, Aher P, Singh I.
europepmc +1 more source
Informed consent for medication in persons with mental retardation and mental illness.
Joan O’Sullivan, Breck Borcherding
openalex +1 more source
The 21 Century Challenge to Autonomy and Informed Consent
Dena S. Davis
openalex +1 more source
ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu +9 more
wiley +1 more source
Beyond the label: ethical and clinical implications of off-label drug use in pediatric emergency care. [PDF]
Colombo M, Plebani A, Agosti M.
europepmc +1 more source
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic +6 more
wiley +1 more source

