Results 61 to 70 of about 3,882,346 (242)
Notice, Consent, and Choice-of-Jurisdiction Clauses in the United States
German Law JournalAlthough choice-of-jurisdiction clauses are routinely enforced by courts in the United States, there are circumstances where they are subject to special scrutiny.
John F. Coyle
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Etikk i Praksis: Nordic Journal of Applied Ethics, 2015 Pedophilia is bad. But how bad is it? And in what ways, and for what reasons, is it bad? This is a thorny issue, and sadly, one seldom discussed by ethicists. In this paper it is argued that pedophilia is bad only because, and only to the extent that, it
Ole Martin Moen
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Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Introducing Susceptibilities: Toward a Cultural Politics of Consent Under Erasure
PhilosophiesThe broad aim of this introduction to a Special Issue on “Susceptibilities: Toward a Cultural Politics of Consent under Erasure” is to broach key questions and research directions that illuminate contemporary public debates about the conditions and ...
Karyn Ball
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Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
The Gatekeeper within: Early Modern English Architectural Tropes of Female Consent
Humanities, 2019 This essay maps out a constellation of early modern English feminine gatekeeper tropes that represent female sexual consent and imagine a gendered Cartesian dualism.
Elisa Oh
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Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Kişiyi Hürriyetinden Yoksun Kılma Suçunun Cinsel Amaçla İşlenmesi
Anadolu Üniversitesi Hukuk Fakültesi Dergisi, 2019 Kişiyi hürriyetinden yoksun kılma fiilinin cinsel amaçla işlenmesi, TCK m.109/1’de düzenlenen suçun temel şekline nazaran cezanın artırılmasını gerektiren nitelikli bir unsurdur (TCK m.109/5).
Reşit Karaaslan
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