Results 131 to 140 of about 4,459,490 (316)
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Apariencia estética y reconciliación: arte y política en Adorno.
Revista de Estudios Sociales, 2009 This essay examines the relation between politics and art in the work of Theodor W. Adorno by analyzing the concepts of reconciliation, artistic truth content, and aesthetic appearance.
Mario Alejandro Molano Vega.
doaj
No functions continuous only at points in a countable dense set
, 2019 We give a short proof that if a function is continuous on a countable dense set, then it is continuous on an uncountable set. This is done for functions defined on nonempty complete metric spaces without isolated points, and the argument only uses that ...
Silva, Cesar E., Wu, Yuxin
core
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Консультативная психология и психотерапия, 2009 The clinic of personal frustration in details analysis in article, attempt to group them, proceeding from phenomenological displays is undertaken.
Belorusov S.A.
doaj
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Dynamic Performance Simulation and Experimental Research of Electric Vehicle Transmission System
Jixie chuandong, 2016 Based on the argument that transmission system parameter is a big consequence on electric vehicle dynamic performance,a parameter matching of electric vehicle is researched,which is aiming at vehicle dynamic performance and combining with the structure ...
Zhou Hongru, Sun Li, Song Jingbin
doaj
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source