Results 131 to 140 of about 1,315,168 (284)
A strengthening of the Consequence Argument for incompatibilism [PDF]
Analysis, 2017 openaire +2 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Religious Belief, Evidentialism, and Skeptical Theism
Cuestiones Teológicas, 2016 The purpose of the article is to develop a line of argument in favor of a religious belief in the existence of God, in such a way that it is possible to hold that: i) it is a rational belief and ii) it is non-dependent on contingent evidence.
Rafael Felipe Miranda Rojas
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Developmental factors as determinants of risk for infections and atopy in childhood
European Respiratory Review, 2005 The nature of the relationship between infections and allergy in children continues to be the subject of vigorous debate, in particular the issue of whether the increased frequency of wheezing respiratory infections in children is a cause or a ...
P. G. Holt
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Another consequence of tanahashi’s argument on best possibility of the grand Furuta inequality
Open Mathematics, 2013 Koizumi Tatsuya, Watanabe Keiichi
doaj +1 more source
What Kind of a Right is the ‘Right to Die’?
European Journal of Mental Health, 2009 Those who argue in favor of a putative right to die rarely look carefully at what kind of a right such a right might be. Yet deciding whether we have a particular right requires understanding what it means to have a right in the first place as well as ...
Constance E. Putnam
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