Results 151 to 160 of about 6,679,166 (303)

Cannabis Use Problems Moderate Daily Associations between Cannabis Consequences and Subsequent Use. [PDF]

J Stud Alcohol Drugs
Dyar C, Rhew IC, Lee CM.
europepmc   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Motivational consequences influence obstacle crossing strategies. [PDF]

Front Hum Neurosci
Schmitt AC, Jendro AM, Champenois I, Raffegeau TE.   +3 more
europepmc   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Psychosocial impact of maternal mortality on bereaved families and health care providers: what do we know? [PDF]

Arch Gynecol Obstet
Alhaj D, Schmock S, Gerhold LL, Wallwiener S, Zdanowicz J, Hanson C, Dudenhausen J, Königbauer J.   +7 more
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Correction: A sustainability framework based on threats, consequences, and solutions (TCS) for managing watershed commons. [PDF]

PLoS One
Camarillo ALQ, Randhir TO.
europepmc   +1 more source

Some consequences of four incapacities [PDF]

, 2010
Peirce, Charles S.
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

High-Intensity Drinking Is Linked to Greater Same-Day Positive and Negative Consequences in Young Adults. [PDF]

J Stud Alcohol Drugs
Merrill JE, López G, Berey BL, Miller MB, Carey KB, Jackson KM, Barnett NP.   +6 more
europepmc   +1 more source