Results 201 to 210 of about 1,698,797 (268)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Clinical Consequences of Inadvertent Intramuscular Administration of Subcutaneous Risperidone Formulation. [PDF]

Case Rep Psychiatry
Ashley E, Aalomerovic A, Blackmer K, El-Mallakh RS.   +3 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The Reverse Risk Register Approach to Understanding Systemic Factors in Risk Analysis and Management Case Studies. [PDF]

Risk Anal
Thekdi S, Aven T.
europepmc   +1 more source

Making microbes matter: evidence for the use of digital storytelling in antimicrobial resistance public engagement. [PDF]

NPJ Antimicrob Resist
McCall B, Hayward A, Lang M, Wilson M, Grailey K, Shallcross L.   +5 more
europepmc   +1 more source

Obstetric Pharmacoethics: An ethical framework for obstetric pharmacology. [PDF]

Eur J Obstet Gynecol Reprod Biol
Eke AC.
europepmc   +1 more source

Psychological consequences of mammography screening recommendations: a prospective cohort study in Iran. [PDF]

BMC Psychol
Hosseini SS, Oreizy HR, Savabi-Esfahani M.   +2 more
europepmc   +1 more source