Results 111 to 120 of about 5,605 (277)

A Moral Normative Approach to Issues of Social Vices in Nigerian Schools

INSTED: Interdisciplinary Studies in Education & Society
Moral instruction in the Nigerian secondary school curriculum is intended to help students develop good moral behaviour. However, the prevalence of deviant and unethical behaviours among students in Nigerian secondary schools raises concerns about the ...
Isidore Agbanero
doaj   +1 more source

BraMARS: An Interpretable Histopathology‐Driven Deep Learning Model for Brain Metastasis Risk Stratification in Surgically Resected Limited‐Stage SCLC

Advanced Science, EarlyView.
This study presents BraMARS, an explainable deep learning model that estimates future brain metastasis risk in surgically resected limited‐stage small‐cell lung cancer using routine H&E‐stained whole‐slide images. By linking model‐attributed spatial histopathology with clinical outcomes and proteomic programs, BraMARS provides a biologically ...
Zijian Yang, Taolue Wang, Shilong Liu, Zicheng Zhang, Yibo Zhang, Fan Yang, Bo Yu, Shuaishuai Gao, Yu Chen, Lin Yang, Meng Zhou   +10 more
wiley   +1 more source

Consequentialism, time, and value

Is consequentialism consistent with common-sense morality? I argue for a negative answer to this question. In Sections 1-4, I develop and defend a definition for “consequentialism.” In Section 5, I attempt to show that, given this definition ...
Killoren, David
core   +3 more sources

Extraterritorial Application as a Problem of the Human Rights Concept

Московский журнал международного права
INTRODUCTION. If the legal recognition of human rights depends on belonging to “all members of the human family”, then the existence of the scope of application of human rights ratione loci is logically contradictory.
Ph. V. Luchkin
doaj   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Tissue‐Agnostic Cellular Morphometric Biomarkers for Risk‐Adapted Management Across Gastrointestinal Precancerous Lesions and Cancers

Advanced Science, EarlyView.
An interpretable, unsupervised artificial intelligence framework identifies a 13‐cellular morphometric biomarker (CMB) signature from routine H&E whole‐slide images. Validated across 2,602 patients, the fixed signature generalizes across colorectal, gastric, and esophageal tissues without retraining, stratifies prognosis and precancerous lesion risk ...
Pin Wang, Chengfei Jiang, April W. Mao, Qi Sun, Yijun Lu, Jingjing Wei, Jamie L. Inman, Susan E. Celniker, Antoine M. Snijders, David W. Threadgill, Allan Balmain, Bo Hang, Hang Chang, Lei Wang, Jian‐Hua Mao   +14 more
wiley   +1 more source

AI Ethics: Should you trust AI with your medical diagnosis?

Journal of Integrative and Innovative Humanities
The use of AI in the medical field leads to one main ethical question: Should you trust AI with your medical diagnosis? To answer this question, one must understand how AI decides, which faces two main problems: The black box and validation data.
Weerawut Rainmanee
doaj  

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Advanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen, Ying Ma, Lixuan Huang, Xin Chen, Fanliang Kong, Zhenzhou Qian, Mingyue Guan, Xinlin Wang, Yanyan Yang, Shasha Zhang, Peng Li, Renjie Chai   +11 more
wiley   +1 more source

The Ethics of Sustainability

BioResources
Sustainability ethics is a relevant topic as we humans become more focused on the implications of “going green.” We all need to think about what sustainability means and the extent to which we need to change our individual behaviors so that its goals can
Martin A. Hubbe, Lucian A. Lucia
doaj  

Epistemic consequentialism: Philip Percival

, 2002
I aim to illuminate foundational epistemological issues by reflecting on 'epistemic consequentialism'—the epistemic analogue of ethical consequentialism.
Percival, P.R.
core   +1 more source