Results 61 to 70 of about 17,676 (306)

Improving the Robustness of Visual Teach‐and‐Repeat Navigation Using Drift Error Correction and Event‐Based Vision for Low‐Light Environments

open access: yesAdvanced Robotics Research, EarlyView.
Visual teach‐and‐repeat (VTR) navigation allows robots to learn and follow routes without building a full metric map. We show that navigation accuracy for VTR can be improved by integrating a topological map with error‐drift correction based on stereo vision.
Fuhai Ling, Ze Huang, Tony J. Prescott
wiley   +1 more source

Actualism, Possibilism, and the Nature of Consequentialism [PDF]

open access: yes, 2020
The actualism/possibilism debate in ethics is about whether counterfactuals of freedom concerning what an agent would freely do if they were in certain circumstances even partly determines that agent’s obligations.
Cohen, Yishai, Timmerman, Travis
core  

Other‐Sacrificing Options [PDF]

open access: yes, 2020
I argue that you can be permitted to discount the interests of your adversaries even though doing so would be impartially suboptimal. This means that, in addition to the kinds of moral options that the literature traditionally recognises, there exist ...
Bader R.   +8 more
core   +1 more source

Hierarchical Targeting of TREM2+ Myeloid Cells via Acid‐Triggered OMVs Reprogram Immunosuppression and Suppress Osteolysis in Bone‐Metastatic TNBC

open access: yesAdvanced Science, EarlyView.
This study developed a hierarchical targeting nanoplatform, siTREM2@ETP‐PEOz‐OMVs, against triple‐negative breast cancer (TNBC) bone metastasis. It precisely delivers therapeutic siTREM2 to monocytes/macrophages within the metastatic niche. This intervention dually regulates cell fate: reprogramming immunosuppressive macrophages and inhibiting ...
Fanglu Chen   +12 more
wiley   +1 more source

Utilitarianism and the idea of university: A short ethical analysis [PDF]

open access: yesFilozofija i Društvo, 2018
The standard objection to the utilitarian vision of morality is that utilitarian so-called “Greatest-Happiness Principle” could justify counter-intuitive practices such as punishing and sacrifice of innocents, breaking of promises and ...
Cekić Nenad
doaj   +1 more source

Speculative Trade and the Value of Public Information [PDF]

open access: yes, 2019
In environments with expected utility, it has long been established that speculative trade cannot occur (Milgrom and Stokey [1982]), and that the value of public information is negative in economies with risk-sharing and no aggregate uncertainty ...
Galanis, S.
core  

Characterizations of Consequentialism and Nonconsequentialism [PDF]

open access: yesJournal of Economic Theory, 2001
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Suzumura, Kotaro, Xu, Yongsheng
openaire   +2 more sources

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

open access: yesAdvanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang   +11 more
wiley   +1 more source

Beyond proximity: Consequentialist Ethics and System Dynamics

open access: yesEtikk i Praksis: Nordic Journal of Applied Ethics, 2017
Consequentialism is a moral philosophy that maintains that the moral worth of an action is determined by the consequences it has for the welfare of a society. Consequences of model design are a part of the model lifecycle that is often neglected.
Erika Palmer
doaj   +1 more source

N4‐acetylcytidine in LncRNA Gm26917 Promotes Translation in Female Germline Stem Cells by Recruiting Ribosomal Protein mRNA via EEF1A1

open access: yesAdvanced Science, EarlyView.
This work establishes that ac4C modification on lncRNA Gm26917 governs its spatial interactions with Rpl10 mRNA, and RBP EEF1A1 mediates the interaction between Gm26917 and Rpl10. It elucidates a novel ac4C‐Gm26917‐EEF1A1‐Rpl10 axis in FGSC maintenance both in vitro and in vivo, and provides a potential molecular target for modulating germ cell ...
Xinyue Li, Xiaopeng Hu, Ji Wu
wiley   +1 more source

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