Results 131 to 140 of about 53,682 (268)

Twenty years of marine systematic conservation planning: a global scoping review for good practices. [PDF]

open access: yesPeerJ
Fabbrizzi E   +17 more
europepmc   +1 more source

Loss of E3 Ubiquitin Ligase RINES via CpG Methylation Relieves Suppression of STAT3 and MYC, Facilitating Multiple Tumorigeneses

open access: yesAdvanced Science, EarlyView.
Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li   +8 more
wiley   +1 more source

Aligning observation to action: Integrated monitoring for tropical seascape conservation and restoration. [PDF]

open access: yesiScience
Carvalho S   +15 more
europepmc   +1 more source

Streptavidins Coordinate Biotin Sequestration and Self‐Resistance Within a Biotin‐Pathway Antibiotic Network

open access: yesAdvanced Science, EarlyView.
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa   +8 more
wiley   +1 more source

Slow Progress Under Brazil's Native Vegetation Protection Law in the Southeastern Amazon. [PDF]

open access: yesEnviron Manage
Almada HK   +4 more
europepmc   +1 more source

Materials‐Guided Gene‐Ionizable Lipid Nanoparticles to Reverse Iron‐Associated Immune Resistance in Renal Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin   +16 more
wiley   +1 more source

A review of coral reef restoration initiatives in the Western Indian Ocean Region. [PDF]

open access: yesPLoS One
Karisa JF   +23 more
europepmc   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

open access: yesAdvanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters   +12 more
wiley   +1 more source

Bridging Conservation Gaps: Evaluating Habitat Mapping Methods for Alpine River Ecosystems. [PDF]

open access: yesEnviron Manage
Winkelhues W   +4 more
europepmc   +1 more source

Reflection about colour in conservation/restoration

open access: yes, 1999
This paper presents some research possibilities related to Colour as a main issue. Some examples of the study of colour in textiles and modern art are given. Architecture related issues are not covered.
openaire   +1 more source

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