Results 51 to 60 of about 53,341 (268)

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Construction of a Desertification Composite Index and Its Application in the Spatiotemporal Analysis of Land Desertification in the Ring-Tarim Basin over 30 Years

Remote Sensing
Desertification is one of the most severe environmental issues facing the world today, and effective desertification monitoring is critical for understanding its dynamics and developing prevention and control strategies.
Lei Xi, Zhao Qi, Yiming Feng, Xiaoming Cao, Mengcun Cui, Jiaxiu Zou, Shiang Feng   +6 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Spatial-Temporal Process of Land Use/Land Cover and Desertification in the Circum-Tarim Basin during 1990–2020

Land
The problem of desertification in the Tarim Basin, an area with a unique geography and climatic conditions, has received extensive research attention not only in China but also around the world.
Xiaoming Cao, Mengchun Cui, Lei Xi, Yiming Feng   +3 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Interactions between phytoplankton and bacterioplankton communities in Caohai plateau lake, revealed by environmental DNA metagenomics

BMC Microbiology
Phytoplankton-bacterioplankton interactions critically influence aquatic ecosystem stability, yet their dynamics remain poorly understood in eutrophic plateau lakes.
Yunchuan Long, Jin Guo, Liangliang Dai, Juan Jiang   +3 more
doaj   +1 more source

Characterizing the composition, metabolism and physiological functions of the fatty liver in Rana omeimontis tadpoles

Frontiers in Zoology, 2019
Background Fat storage is required for the life cycle of many organisms. The primary fat depot for most vertebrates is white adipose tissue. However, in primitive vertebrates (e.g., agnathan group and elasmobranchs), the liver is usually responsible for ...
Wei Zhu, Meihua Zhang, Liming Chang, Wenbo Zhu, Cheng Li, Feng Xie, Huan Zhang, Tian Zhao, Jianping Jiang   +8 more
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

A Restoring Paradigm of Estuarine Wetland Based on Resilience

Ecosystem Health and Sustainability
Estuarine wetlands provide various critical ecosystem services, including providing habitats for organisms, biodiversity conservation, and nutrient cycling and are important regions for human life and economic development.
Henian Wang, Manyin Zhang, Lijuan Cui, Ziliang Guo, Daan Wang, Weiwei Liu   +5 more
doaj   +1 more source

Unveiling the Occupational Exposure to Microbial Contamination in Conservation-Restoration Settings. [PDF]

Microorganisms, 2022
Viegas C, Cervantes R, Dias M, Gomes B, Pena P, Carolino E, Twarużek M, Kosicki R, Soszczyńska E, Viegas S, Caetano LA, Pinheiro AC.   +11 more
europepmc   +1 more source