Results 1 to 10 of about 523,622 (219)

The Old Conservation, the New Conservation, and the Future of Conservation [PDF]

open access: yesConservation Biology, 2016
Fil: Lichtenstein, Gabriela. Consejo Nacional de Investigaciones Cientificas y Tecnicas; Argentina. Secretaria de Cultura de la Nacion. Direccion Nacional de Cultura y Museos.
openaire   +2 more sources

Disruptive Conservation: Challenging Conservation Orthodoxy [PDF]

open access: yesStudies in Conservation, 2021
This paper takes the position that our current treatments that involve infilling with a neutral rather than matched colour are deceptive to the viewer and that such deliberate mediation through the act of conservation can deny the viewer an authentic understanding of the heritage object.
Eleanor Sweetnam, Jane Henderson
openaire   +1 more source

Conservation of parasites

open access: yesInternational Journal for Parasitology: Parasites and Wildlife, 2021
Windsor, Donald A. (2021): Conservation of parasites. International Journal for Parasitology: Parasites and Wildlife 14: 137-137, DOI: 10.1016/j.ijppaw.2021.01.011, URL: http://dx.doi.org/10.1016/j.ijppaw.2021.01 ...
openaire   +3 more sources

THE CONSERVATION OF ENERGY AND CONSERVATIVE GYNÆCOLOGY. [PDF]

open access: yesJournal of the American Medical Association, 1885
Read before the Boston Gynaecological Society. There may seem to be some incongruity in the caption of this paper, a juxtaposition of terms that can have no possible relation each to the other; or, it may be, an entire misconception of what is meant by the Conservation of Energy.
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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