Results 111 to 120 of about 101,898 (241)

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source

Balancing land use for conservation, agriculture, and renewable energy. [PDF]

Nat Commun
Brock C, Roehrdanz PR, Beringer T, Chaplin-Kramer R, Enquist BJ, Frazier AE, Johnson JA, Kennedy CM, Kiesecker J, Larsen AE, Loyola R, Marquet PA, Neugarten RA, Oakleaf JR, Roopsind A, Schuster R, Williams DR, Wu GC, Zvoleff A, Hannah L.   +19 more
europepmc   +1 more source

A mixed-methods evaluation of capacity strengthening within an international conservation agriculture research consortium. [PDF]

F1000Res, 2023
Duda K, D'Artibale A, Moombe M, Lark RM, Pulford J.   +4 more
europepmc   +1 more source

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

Advanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong, Siang Chen, Maolin Li, Meng Wang, Hailin Zhang, Bolun Zhou, Zhenhua Xie, Chen Wang, Peng Gao, Jianjun Luo, Hanchun Yang, Runsheng Chen, Dongdong Zhang, Jie Li, Jun Han   +14 more
wiley   +1 more source

Conservation agriculture enhances soil and water conservation and crop yield in the Ethiopian highlands. [PDF]

PLoS One
Alemie TC, Wubet A, Fentahun M, Worku M, Awoke A, Ambaw Z, Amare T, Zegeye AD.   +7 more
europepmc   +1 more source

Adaptive Responses of Tropical Crops: A Multi‐Scale Omics Integrated Perspective

Advanced Science, EarlyView.
Tropical crops integrate genomic, morphological, physiological, and ecological adaptations to thrive under extreme and variable environments. This review highlights how natural selection, domestication, and breeding shape stress resilience, resource‐use strategies, and productivity in sugarcane, banana, cassava, rubber and oil palm, offering new routes
Peilin Wang, Chenhui Li, Dongjiao Wang, Qibin Wu, Zhen Zeng, Huiming Guo, Han Cheng, Songbi Chen, Hongxing Cao, Hongmei Cheng, Jianghui Xie, Youxiong Que   +11 more
wiley   +1 more source

Short-term responses in weed spatial patterns during early adoption of conservation agriculture practices. [PDF]

Pest Manag Sci
Rozenberg G, Carmel Y, Eshel G, Blank L.
europepmc   +1 more source

Herbicide Metabolic Resistance in Poaceae Plants via the GA‐GID1/DELLA‐DOF2‐P450s Module

Advanced Science, EarlyView.
Plant hormone signaling modulates herbicide resistance in Echinochloa crus‐galli. The GA–DELLA–DOF2 cascade directly activates P450 detoxification genes in two Poaceae species, uncovering a core mechanism of metabolic herbicide resistance. ABSTRACT Barnyard grass (Echinochloa crus‐galli) is one of the world's most important weeds, and the evolution of ...
Junzhi Wang, Jiale Qi, Lin Wei, Qin Yu, Zhongyuan Liu, Lianyang Bai, Lang Pan   +6 more
wiley   +1 more source

Conservation agriculture enhances ecosystem services and sustainability of the system over conventional agriculture. [PDF]

Sci Rep
Mandal N, Maity PP, Mridha N, Das TK, Bandyopadhyay KK, Pillai SN, Biswas A.   +6 more
europepmc   +1 more source

Quantifying the Adoption of Conservation Agriculture: Development and Validation of the Conservation Agriculture Appraisal Index

Agricultural Systems, 2023
Laura I. Ruiz-Espinosa, Nele Verhulst, Floris van Ogtrop, Rebecca Cross, Bram Govaerts, Harm van Rees, Richard Trethowan   +6 more
openaire   +1 more source