Results 181 to 190 of about 2,343,705 (241)

Modulation of Animal Gut Health by Milk Oligosaccharide

Animal Research and One Health, EarlyView.
This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen, Nana Jing, Shiyu Tao, Mingyue Fei, Wentao Lv, Hua Yang, Yingping Xiao, Haiqin Wu   +7 more
wiley   +1 more source

The sRNA vvrr1 Modulates the VarS/VarA‐Csr System via LeuO to Regulate Biofilm Formation and Virulence in Vibrio alginolyticus

Animal Research and One Health, EarlyView.
vvrr1, a small RNA, post‐transcriptionally represses the transcriptional regulator LeuO, which directly inhibits the VarS/VarA two‐component system. This triggers a Csr cascade that relieves LuxO repression, ultimately modulating exopolysaccharide production to control biofilm formation and virulence in Vibrio alginolyticus.
Theerakamol Pengsakul, Lei Wen, Lingmin Zhao, Bei Huang, Jiang Zheng, Binfu Xu, Lixing Huang   +6 more
wiley   +1 more source

Cross‐Species Single‐Cell Comparative Analysis Reveals Gluconeogenic Features of Hepatocytes in Ruminants

Animal Research and One Health, EarlyView.
In this study, we used cross‐species comparisons to identify ruminant hepatocyte features. We also identified potential genes and TFs involved in coordinating gluconeogenesis in ruminant hepatocytes. By integrating single‐cell data with population genetic analyses, we further identified candidate genetic variation in glucose metabolism and ...
Yaqi Zhou, Wuqiang Huo, Yingran Liu, Yihang Liu, Fei Wang, Tao Shi, Yu Jiang   +6 more
wiley   +1 more source

Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing

Animal Research and One Health, EarlyView.
Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley   +1 more source

Cumulative Reproductive‐Lactation Burdens Induce a Systemic Immunometabolic Trade‐Off Between Milk Yield and Mammary Health of Dairy Cows

Animal Research and One Health, EarlyView.
A population‐scale longitudinal transcriptomic atlas reveals how lactation stage and parity reshape systemic gene regulation in dairy cows. Multiomics‐inspired analyses uncover dynamic immune and metabolic adaptations that contribute to reproductive longevity and sustained productivity across the bovine lifespan.
Yangyang Shen, Zhenjiang An, Yingying Jiang, Zijian Huang, Kunlin Chen, Yundong Gao, Jianbin Li, Shuwen Xia, Huili Wang   +8 more
wiley   +1 more source

Potential Conservation Laws [PDF]

Journal of Mathematical Physics, 2008
We prove that potential conservation laws have characteristics depending only on local variables if and only if they are induced by local conservation laws. Therefore, characteristics of pure potential conservation laws have to essentially depend on potential variables. This statement provides a significant generalization of results of the recent paper
Michael Kunzinger, Roman O Popovych
exaly   +5 more sources

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On the conservation laws of PDEs

Reports on Mathematical Physics, 1988
The covariance of methods for obtaining conservation laws for nonlinear partial differential equations is studied [the second author, Riv. Nuovo Cim. 5, No.4, 1-122 (1982; see the review above) and \textit{A. M. Vinogradov}, J. Math. Anal. Appl. 100, 41-129 (1985; Zbl 0548.58015)].
MARINO V, PRASTARO, Agostino
openaire   +3 more sources

On the optimization of a conservation law

Calculus of Variations and Partial Differential Equations, 2004
Consider the Cauchy problem for a conservation law and assume that an integral functional on its solution is defined. In this note we obtain an Euler-Lagrange equation for the stationary points of this functional. An application to the optimal management of traffic flows is considered.
COLOMBO, Rinaldo Mario, GROLI ALESSANDRO
openaire   +1 more source

On Stability of Conservation Laws

SIAM Journal on Mathematical Analysis, 1999
The authors consider the Cauchy problem for a nonlinear perturbation in conservation form of a linear system that may be parabolic, hyperbolic or mixed. The system also has conservative forcing terms that decay to zero for large time. The issue examined is that of nonlinear stability, for which the solution with zero initial data remains smooth and ...
Kreiss, Gunilla, Kreiss, Heinz-Otto, Lorenz, Jens   +2 more
openaire   +2 more sources

Hyperbolic Conservation Laws

Oberwolfach Reports, 2005
The conference was organized by Constantine Dafermos (Providence), Dietmar Kröner (Freiburg), Randy LeVeque (Seattle). 44 scientists from 9 countries participated in this workshop. During the conference we had 22 main lectures and on Tuesday and Thursday evening 10 short informal contributions.
Constantine Dafermos, Dietmar Kröner, Randy Leveque   +2 more
openaire   +1 more source