Results 91 to 100 of about 1,065,128 (300)

Evaluating the Utilities of Foundation Models in Single‐Cell Data Analysis

Advanced Science, EarlyView.
This study delivers the first systematic, task‐level evaluation of single‐cell foundation models across eight core analytical tasks. By benchmarking 10 leading models with the scEval framework, it reveals where foundation models truly add value, where task‐specific methods still dominate, and provides concrete, reproducible guidelines to steer the next
Tianyu Liu, Kexing Li, Yuge Wang, Hongyu Li, Hongyu Zhao   +4 more
wiley   +1 more source

Indirect Effects of Eco-labelling of agricultural products on Natural Resources [PDF]

The implementation of eco-labelling schemes for agricultural and food products may represent an opportunity to enhance production technologies compatible with the sustainable economic approach.
Prosperi, Maurizio, Viscecchia, Rosaria
core   +1 more source

Eksklusi Atas Nama Konservasi (Studi Kasus Masyarakat Sekitar/dalam Kawasan Taman Nasional Ujungkulon Banten) [PDF]

, 2013
This paper elaborate on the issue of conservation, agrarian conflict and exclusion communities around / in the conservation area of the National Park Ujungkulon (TNUK) Banten.
Cahyono, E. (Eko)
core  

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Exploring the spatiotemporal patterns and non-linear influencing mechanisms of ecosystem service values: a comparison between urban and rural areas at the municipal scale

Ecological Indicators
Ecosystem service value (ESV) is crucial for sustainable development. However, the spatiotemporal patterns of different types of ESV and their non-linear responses to influencing factors remained unclear at the municipal scale. By adopting an urban-rural
Zhiyu Fan, Yun Wang, Qingming Zhan, Zhihao Sun, Chun Wu   +4 more
doaj   +1 more source

Invasive Species Management and Buffer Outreach on Goss Farm, Rye, NH [PDF]

, 2011
The Goss Farm was permanently protected in November of 2010 with assistance from the USDA, Natural Resources Conservation Service Farm and Ranch Lands Protection Program (FRPP) and is located directly adjacent to the Awcomin Salt Marsh, in Rye, New ...
Rockingham County Conservation District
core   +1 more source

NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks

Advanced Science, EarlyView.
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang, Yizhou Zeng, Yunfeng Chen, Zhengqing Li, Salma Mbarouk Omar, Shengwei Zhong, Ping Liu, Zhanhong Zheng, Gaofeng Cai, Xiaona Gao, Xiaoquan Guo   +10 more
wiley   +1 more source

Restriction of Individual Branched‐Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice

Advanced Science, EarlyView.
Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija, Cara L. Green, Michelle M. Sonsalla, Izabelle Marie F. Le, Fan Xiao, Sarah Yandell, Mariah F. Calubag, Michaela E. Trautman, Anna Tobon, Ryan Matoska, Chung‐Yang Yeh, Charles I. Opara, Isaac Grunow, Diana Vertein, Sophia Schlorf, Bailey A. Knopf, Michael J. Rigby, David A. Harris, Mark P. Keller, Alan D. Attie, Luigi Puglielli, Cholsoon Jang, Dudley W. Lamming   +22 more
wiley   +1 more source

Peran Dewan Perwakilan Daerah Republik Indonesia dalam Konservasi Sumber Daya Alam Berdasarkan Undang-undang Nomor 27 Tahun 2009 (Studi Kasus di Jawa Tengah) [PDF]

, 2011
Natural Resources represent the element from environment. Environmental crisis as its uneven effect of natural resources exploiting bear the opinion to do the conservation.
Herawati, R. (Ratna)
core