Results 211 to 220 of about 5,963,485 (334)

Conservation Planning for Promoting Ecosystem Service Provisioning Outside Protected Area Networks. [PDF]

Ecol Evol
Tarimo FG, Moyo F, Kelly C, Munishi LK.
europepmc   +1 more source

A Non‐Mitophagy Activity of BNIP3L/NIX in Amygdala Glutamatergic Neurons is Essential for Contextual Fear Memory Formation

Advanced Science, EarlyView.
Contextual fear conditioning induces BNIP3L‐dependent mitochondrial fission in glutamatergic neurons of the BLA, independently of mitophagy. Loss of BNIP3L elevates Drp1Ser637 phosphorylation, thereby suppressing mitochondrial fission, compromising ATP production, and attenuating excitatory synaptic transmission.
Xingxian Zhang, Xinlei Mo, Xinyu Zhou, Xiaoliang Liu, Guizhi Li, Songhui Hu, Yangyang Lu, Chenze Zhu, Jinxi Feng, Zhitong Chen, Weiwei Hu, Yihui Cui, Zhong Chen, Xiangnan Zhang   +13 more
wiley   +1 more source

Systematic conservation planning for nature recovery. [PDF]

Bioscience
Baker DJ, Gaston KJ, Metcalfe K, Maclean IMD.   +3 more
europepmc   +1 more source

Plant diversity and community analysis of Sele-Nono forest, Southwest Ethiopia: implication for conservation planning. [PDF]

Bot Stud, 2022
Kefalew A, Soromessa T, Demissew S.
europepmc   +1 more source

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Doehl et al. discovered an adaptive neuroimmune mechanism that induces itch in tick‐exposed guinea pigs, enabling rapid tick removal. This itch‐induced tick removal (IITR) is mediated by an adaptive cellular immune response and is independent of IgG, IgE, or TRPV1.
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

Species richness prediction and priority conservation planning for rare Michelia species in China. [PDF]

Sci Rep
Tang J, Chen Z, Yin X, Teng J, Gao W, Liu Y, Li X.   +6 more
europepmc   +1 more source

Genetic Diagnosis and Discovery Enabled by Large Language Models

Advanced Science, EarlyView.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu, Khaled Saab, Weida Liu, Zhouqing Fang, Zhuanfen Cheng, Svetolik Spasic, Maja Djurisic, Hiroaki Mohri, Wenlong Ren, Anil Palepu, Juraj Gottweis, Alan Karthikesalingam, Kavita Kulkarni, Annalisa Pawlosky, Devon Bonner, Elijah Kravets, Shruti Marwaha, Hector R. Mendez, Matthew T. Wheeler, Jonathan A. Bernstein, Undiagnosed Diseases Network, Cheng‐Yu Tsai, Chen‐Chi Wu, Konstantina M. Stankovic, Vivek Natarajan, Gary Peltz   +25 more
wiley   +1 more source

Important Shark and Ray Areas can inform conservation planning in the Mediterranean and Black Seas. [PDF]

iScience
Rohner CA, Richardson AJ, García-Rodríguez E, Charles R, Batlle-Morera A, Bortoluzzi JR, Mouton TL, Notarbartolo di Sciara G, Armstrong AO, Everett JD, Bakiu R, Barash A, Bariche M, Başusta N, Bousquet C, Ćetković I, Giovos I, Guallart J, Milazzo M, Morey G, Naasan Aga-Spyridopoulou R, Niedermueller S, Serena F, Shakman E, Soldo A, Jabado RW.   +25 more
europepmc   +1 more source

Evaluating surrogates of genetic diversity for conservation planning. [PDF]

Conserv Biol, 2021
Hanson JO, Veríssimo A, Velo-Antón G, Marques A, Camacho-Sanchez M, Martínez-Solano Í, Gonçalves H, Sequeira F, Possingham HP, Carvalho SB.   +9 more
europepmc   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source