Results 91 to 100 of about 771,843 (288)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Determinants of cereal diversity in communities and on household farms of the Northern Ethiopian Highlands: [PDF]

open access: yes
"On farm conservation of crop diversity poses obvious policy challenges in terms of the design of appropriate incentive mechanisms and possible trade-offs between conservation and productivity.
Benin, Samuel   +4 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Conservation Practices for Personal Protective Equipment: A Systematic Review with Focus on Lower-Income Countries. [PDF]

open access: yesInt J Environ Res Public Health, 2023
Thiel CL   +11 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Multiple-land use practices in transfrontier conservation areas: the case of Greater Mapungubwe straddling parts of Botswana, South Africa and Zimbabwe

open access: yesBulletin of Geography. Socio-Economic Series, 2016
Transfrontier Conservation Areas (TFCAs) have recently emerged as the 21st century approach to managing protected areas in southern Africa. Unlike national parks and other protected areas that place emphasis only on the protection of plant and animal ...
Sinthumule Ndidzulafhi Innocent
doaj   +1 more source

An Overview of the Effectiveness of Agricultural Conservation Practices for Water Quality Improvement. [PDF]

open access: yesJ ASABE, 2022
Yuan Y   +6 more
europepmc   +1 more source

"Cost Effective Conservation Planning: Twenty Lessons from Economics" [PDF]

open access: yes
Economists advocate that the billions of public dollars spent on conservation should be allocated to achieve the largest possible social benefit. This is what we term “cost-effective conservation”-- a process that incorporates both benefits and costs ...
Joshua M.Duke   +2 more
core  

Carbon credits and conservation practices [PDF]

open access: yes, 2004
Carbon and the \u27carbon cycle\u27. Over the past century, CO2 levels have risen significantly. There is considerable debate about the reasons -- whether it\u27s a natural cycle or the result of increased CO2 emissions due to human activities-- but ...
Al-Kaisi, Mahdi   +3 more
core   +2 more sources

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