Results 111 to 120 of about 771,843 (288)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

"No-Till" Farming Is a Growing Practice [PDF]

open access: yes
Most U.S. farmers prepare their soil for seeding and weed and pest control through tillage—plowing operations that disturb the soil. Tillage practices affect soil carbon, water pollution, and farmers’ energy and pesticide use, and therefore data on ...
Ebel, Robert M.   +2 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

The development of sustainable cropping systems in the highlands of South-East Asia: general lessons for development projects [PDF]

open access: yes, 2005
Hosted by 'Open Journal Systems'Soil conservation in the highlands of South-East Asia is essential for sustainable agro-environmental development. The effectiveness of soil conservation treatments developed in runoff plots was investigated in farmer ...
Fullen, Michael A.
core   +2 more sources

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Soil conservation practices in a watershed in Southern Brazil

open access: yesAnais da Academia Brasileira de Ciências
: The aim of this study was to determine how often rural farmers in a watershed use no-tillage systems combined with crop rotation, contour farming and agricultural terraces.
TIAGO S. TELLES   +4 more
doaj   +1 more source

Adoption and diffusion of no tillage practices in Southern Spain olive groves [PDF]

open access: yes
This paper analyses the process of adoption of no tillage in South-eastern Spain’s olive groves. Olive tree groves in South-eastern Spain’s mountainous areas are subject to a high risk of soil erosion, which is the main environmental problem for this ...
Calatrava-Requena, Javier   +1 more
core   +1 more source

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