Results 81 to 90 of about 771,843 (288)

Exploring the Knowledge, Attitudes, and Practices (KAP) of locals towards ecotourism in Samar, Philippines: Insights for sustainable development

Ho Chi Minh City Open University Journal of Science - Social Sciences
The pandemic highly impacted the ecotourism sector. And the income of these sectors also suffered from the health crisis. This paper explores the Knowledge, Attitudes, and Practices (KAP) of locals in the countryside of Samar, Philippines.
Jonas Pacios Fabillar, Jose Jake Ojeda Uy, Mario Cabarrubias Daguinod   +2 more
doaj   +1 more source

Assessment of the determinants that influence the adoption of sustainable soil and water conservation practices in Techiman Municipality of Ghana

International Soil and Water Conservation Research, 2019
This paper assesses the relationship between farmer characteristics and the degree to which nine soil and water conservation practices (SWCPs) are adopted by 300 maize farmers in Techiman Municipality, Ghana.
Kwasi Adjepong Darkwah, Joana Deladem Kwawu, Frank Agyire-Tettey, Daniel Bruce Sarpong   +3 more
doaj   +1 more source

Adoption of Soil Erosion Control Practices in Southern Spain Olive Groves [PDF]

This paper presents results from a survey carried out in 2005 among 147 olive tree farmers from the Alto Genil River Basin in Southern Spain regarding the adoption of soil conservation and management practices.
Calatrava-Leyva, Javier, Franco, Juan Agustin   +1 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Autonomous conservation: A literature review of concepts, local practices, and their relevance in the tropics

Global Ecology and Conservation
Official conservation activities are absent in many tropical regions, but local people living in and around these areas nonetheless engage in practices that contribute to conservation objectives.
Indah Waty Bong, Manuel Boissière, Dyah Rahmawati Hizbaron, Muhammad Anggri Setiawan, Douglas Sheil   +4 more
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Analysis of soil management and water conservation practices adoption among crop and pasture farmers in humid-south of the United States

International Soil and Water Conservation Research, 2018
Nutrient management, water quality protection, and irrigation efficiency top the list of on-farm resource concerns indicating a need to address them through conservation strategies.
Naveen Adusumilli, Hua Wang
doaj   +1 more source

Adoption of Conservation-Tillage Practices in Cotton Production [PDF]

Replaced with revised version of paper 10/23/07.conservation tillage, cotton, genetically modified seed, herbicide-resistant cotton, stacked-gene cotton, simultaneous logit model, single-equation logit model, technology adoption, Crop Production ...
Banerjee, Swagata (Ban), Hogan, Robert J., Jr., Johnson, Jason L., Larson, James A., Martin, Steven W., Paxton, Kenneth W., Reeves, Jeanne M., Roberts, Roland K.   +7 more
core   +1 more source