Results 91 to 100 of about 1,820,994 (309)
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Wildbook: Crowdsourcing, computer vision, and data science for conservation
, 2017 Photographs, taken by field scientists, tourists, automated cameras, and incidental photographers, are the most abundant source of data on wildlife today.
Berger-Wolf, Tanya Y. +9 more
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A local grid refinement technique based upon Richardson extrapolation [PDF]
, 1997 A grid-embedding technique for the solution of two-dimensional incompressible flows governed by the Navier-Stokes equations is presented. A single coarse grid covers the whole domain, and local grid refinement B carried out in the regions of high ...
Bai +31 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Social Licence for Marine Conservation Science
Frontiers in Marine Science, 2018 Marine environments are complex and dynamic social-ecological systems, where social perceptions of ocean stewardship are diverse, resource use is potentially unsustainable, and conservation efforts rely strongly on public support or acceptance ...
Rachel Kelly +5 more
doaj +1 more source
Policy Relevant Conservation Science [PDF]
Conservation Letters, 2015 Game, Edward T. +2 more
openaire +3 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Prospects and challenges for social media data in conservation science
Frontiers in Environmental Science, 2015 Social media data have been extensively used in numerous fields of science, but examples of their use in conservation science are still very limited. In this paper, we propose a framework on how social media data could be useful for conservation science ...
Enrico eDi Minin +4 more
doaj +1 more source
The Official Student Newspaper of UAS [PDF]
, 2013 UAS Answers -- UAS in Brief -- UAS Alumni and Friends Spring Dinner -- One Campus One Book ‘Being Caribou’ used in e-Learning course -- Need help with your taxes? -- Post-break career service events -- Pick. Click. Give.
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source