Results 121 to 130 of about 1,820,994 (309)

Reducing publication delay to improve the efficiency and impact of conservation science. [PDF]

PeerJ, 2021
Christie AP, White TB, Martin PA, Petrovan SO, Bladon AJ, Bowkett AE, Littlewood NA, Mupepele AC, Rocha R, Sainsbury KA, Smith RK, Taylor NG, Sutherland WJ.   +12 more
europepmc   +1 more source

Determinants of cereal diversity in communities and on household farms of the Northern Ethiopian Highlands: [PDF]

"On farm conservation of crop diversity poses obvious policy challenges in terms of the design of appropriate incentive mechanisms and possible trade-offs between conservation and productivity.
Benin, Samuel, Ehui, Simeon, Gebremedhin, Berhanu, Pender, John L., Smale, Melinda   +4 more
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Automating the extraction of information from a historical text and building a linked data model for the domain of ecology and conservation science. [PDF]

Heliyon, 2022
Nundloll V, Smail R, Stevens C, Blair G.
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Comparative hydrolysis analysis of cellulose samples and aspects of its application in conservation science. [PDF]

Cellulose (Lond), 2021
Becker M, Ahn K, Bacher M, Xu C, Sundberg A, Willför S, Rosenau T, Potthast A.   +7 more
europepmc   +1 more source

Linking 'citizen scientists' to professionals in ecological research, examples from Namibia and South Africa [PDF]

, 2009
The use of trained members of the public (‘citizen scientists’) to help monitor and collect data in science-driven environmental research projects is not a new concept e.g.
Araya, Yoseph N., Schmiedel, Ute, von Witt, Caitlin   +2 more
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source