Results 121 to 130 of about 28,629,234 (254)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

THE QUANTITATIVE ANALYSIS FOR THE CHOICE INDEXES FOR SPECIES OF FUEL WOOD

open access: yesShuitu baochi yanjiu, 1992
This paper chose six charactic indexes,yield,fuel value,water potential,tissue water content,ratio of free water to bound water and natural saturation deficit,according to the charactersitic that fuel wood plants should have higher and drought resistance.
Northwestern Institute of Soil and Water Conservation under the Chinese Academy of Science and Ministry of Water Conservancy YangLing·Shaanxi·712100)
doaj  

Conservation Connection: Freehold Soil Conservation District Newsletter, Fall 2007

open access: yes, 2007
This newsletter from the Freehold Soil Conservation District contains the following articles: Trout in the Classroom 2007; William "Bill" Schauer 1929-2007; 2008 Poster Contest: Water is Life; 2008 Envirothon for High School Students; Buscaglia Named ...

core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

The importance of preventive conservation in the history of the conservation and restoration of cultural property

open access: yes, 2018
Se muestra un proyecto puesto en marcha en el marco docente de la asignatura Teoría e Historia de la Conservación y Restauración de Bienes Culturales del Grado de Conservación y Restauración de la Facultad de Bellas Artes de la Universidad de Sevilla ...
Ruiz-de-Lacanal, María-Dolores   +4 more
core   +1 more source

Statistical matching for conservation science. [PDF]

open access: yesConserv Biol, 2020
Schleicher J   +5 more
europepmc   +1 more source

Conservation practice could benefit from routine testing and publication of management outcomes [PDF]

open access: yes, 2013
Effective conservation requires a step change in the way practitioners can contribute to science and can have access to research outputs. The journal Conservation Evidence was established in 2004 to help practitioners surmount several obstacles they ...
Walsh, Jessica   +13 more
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Three lessons conservation science can learn from the COVID-19 pandemic. [PDF]

open access: yesConserv Biol, 2020
Buxton RT   +7 more
europepmc   +1 more source

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