Results 161 to 170 of about 6,505,732 (343)
PICES Press, Vol. 21, No. 2, Summer 2013 [PDF]
, 2013 •The 2013 Inter-sessional Science Board Meeting: A Note from the Science Board Chairman (pp. 1-4) •ICES/PICES Workshop on Global Assessment of the Implications of Climate Change on the Spatial Distribution of Fish and Fisheries (pp.
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Mismatches between conservation science and practice [PDF]
, 2004 Griffiths, Richard A.
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〔報告〕日本の「遺跡保存」の歴史と「保存科学」の役割 [PDF]
, 2013 History of the conservation of ruins in Japan is reviewed as a part of the history of conservation science in Japan. Concept of protecting traces of past people can be detected even before the Meiji Restoration.
朽津 信明
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Doing social science with conservation: co-reflexivity on the project model in conservation
OryxThe conservation sector increasingly values reflexivity, in which professionals critically reflect on the social, institutional and political aspects of their work.
Viola Schreer +6 more
doaj +1 more source
Summary Report: Project Terra Research Meeting [PDF]
, 2000 Developing the conservation of earthen architectural Heritage -- as a science, a field of study, a professional practice, and a social endeavor -- is the overall objective of Project ...
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Citizen Science Offers Untapped Potential for Conservation Through Research Flexibility
Conservation LettersThe dynamic nature of research prioritization calls for flexibility in conservation research, yet there are many barriers to research flexibility.
Caitlin P. Mandeville
doaj +1 more source