Results 141 to 150 of about 336,840 (304)
Conservation of amphibians and reptiles in Indonesia: issues and problems
, 2006 Indonesia is an archipelagic nation comprising some 17,000 islands of varying sizes and geological origins, as well as marked differences in composition of their floras and faunas.
Iskandar, Djoko T., Erdelen, Walter R.
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FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
An integrated planning approach for the conservation of freshwater ecosystems in South Africa
, 2009 Includes bibliographical references (p. 125-140).Freshwater ecosystems underpin the fabric of society and the environment, providing essential ecosystem services such as water and food, upon which all human beings depend.
Amis, Mao Angua.
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FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
Conservation education in shark ecotourism
, 2015 Sharks, as top predators, are vital a healthy marine ecosystem. Sharks regulate species abundance, distribution, and diversity, which in turn can impact the health of marine habitats.
Golby, Craig Allan
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FEBS Open Bio, EarlyView.The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
The conservation status of hoolock gibbons in Myanmar [PDF]
, 2013 Hoolock gibbons are small apes of South-east Asia, and Myanmar is believed to be their last stronghold. In Bangladesh, India, and China, most forests supporting the hoolock gibbons are small and highly fragmented. Myanmar, in contrast, is thought to have
Geissmann, Thomas +5 more
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MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
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