Results 181 to 190 of about 5,247,859 (404)

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Understanding the color variability and resolving taxonomic confusion in the sea cucumber Isostichopus badionotus (Echinodermata, Holothuroidea): a revision of the genus Isostichopus

European Journal of Taxonomy
Isostichopus badionotus (Selenka, 1867) is distributed in the Atlantic Ocean. It has been recognized as a species with highly variable intraspecific coloration.
Giomar H. Borrero-Pérez, Francisco A. Solís-Marín, Harilaos Lessios   +2 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Historical Range, Current Distribution, and Conservation Status of the Swift Fox, <em>Vulpes velox</em>, in North America

, 2009
Marsha A. Sovada, Robert O. Woodward, Lawrence D. Igl   +2 more
openalex   +2 more sources

Floristic Diversity and Conservation Status of Non-Reserve Forest Area of Kachchh District, Gujarat

, 2022
Vinay M. Raole
openalex   +1 more source

Current Status and Future Prospects of Applying Bioinspired Superhydrophobic Materials for Conservation of Stone Artworks [PDF]

, 2020
Yijian Cao, Antonella Salvini, Mara Camaiti   +2 more
openalex   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Conservation status of New Zealand reptiles, 2012 [PDF]

: The conservation status of all known New Zealand reptile taxa was reassessed using the New Zealand Threat Classification System (NZTCS). A full list is presented, along with a statistical summary and brief notes on the most important changes. This list
Rod Hitchmough
core  

Distribution and Status of the Kiamichi Shiner, Nottropis ortenburgeri Hubbs (Cyprinidae) [PDF]

, 2005
The Kiamichi shiner, Notropis ortenburgeri, a diminuitive, silvery, upland stream fish in southwestern Arkansas and eastern Oklahoma was studied from 1999-2001 to determine its distribution, habitat, and conservation status in Arkansas and Oklahoma ...
Robison, Henry W.
core  

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source