Results 301 to 310 of about 969,400 (343)

Molecular Mechanisms of Extracellular Vesicle Biogenesis and Their Impact on the Design of Custom EVs

open access: yesAdvanced Healthcare Materials, EarlyView.
Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz   +2 more
wiley   +1 more source

An Organ‐on‐Chip Platform for Strain‐Controlled, Tissue‐Specific Compression of Cartilage and Mineralized Osteochondral Interface to Study Mechanical Overloading in Osteoarthritis

open access: yesAdvanced Healthcare Materials, EarlyView.
A mechanically active OsteoChondral Unit (OCU)‐on‐Chip platform mimicking the OCU's functional anatomy and the strain gradient across the osteochondral interface is presented. Upon compartment‐specific hyperphysiological compression, the model replicates mechanisms observed in osteoarthritis (OA) progression, such as calcium crystal accumulation ...
Andrea Mainardi   +10 more
wiley   +1 more source

Engineering a Human‐Sized Common Bile Duct Prototype with Regenerative Potential: In Vitro Evaluation of Mechanics, Function, Degradation, and Immune Modulation

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a multiphasic bile duct construct composed of biocompatible materials and cells, featuring an inner layer that supports biliary epithelium growth, a middle layer providing mechanical strength, and an outer cell‐permissive layer designed to support future in vivo integration.
Mattia Pasqua   +9 more
wiley   +1 more source

Computational Modeling of Reticular Materials: The Past, the Present, and the Future

open access: yesAdvanced Materials, EarlyView.
Reticular materials are advanced materials with applications in emerging technologies. A thorough understanding of material properties at operating conditions is critical to accelerate the deployment at an industrial scale. Herein, the status of computational modeling of reticular materials is reviewed, supplemented with topical examples highlighting ...
Wim Temmerman   +3 more
wiley   +1 more source

Manipulating Ferroelectric Topological Polar Structures with Twisted Light

open access: yesAdvanced Materials, EarlyView.
We demonstrate dynamic control of ferroelectric order in quasi‐2D CsBiNb2O7 using twisted ultraviolet light carrying orbital angular momentum. Our approach harnesses non‐resonant multiphoton absorption and induced strain to modulate topological of ferroelectric polarization textures.
Nimish P. Nazirkar   +10 more
wiley   +1 more source

Acoustic Moiré Flat Bands in Twisted Heterobilayer Metasurface

open access: yesAdvanced Materials, EarlyView.
This research proposes a heterobilayer moiré acoustic metasurface using two distinct lattice structures. The heterobilayer design contributes to divergent dispersion curves for the upper and lower layers and allows for greater flexibility in tuning their hybridization through interlayer twisting.
Shida Fan   +7 more
wiley   +1 more source

Phonon Driven Ferroelectricity and Raman Active Modes in Hybrid Organic‐Inorganic Perovskites

open access: yesAdvanced Materials, EarlyView.
Ferroelectric domains, a hallmark of ferroelectricity, are studied using temperature‐dependent Raman spectroscopy to uncover characteristic phonons associated with ferroelectric phase transitions in different n‐value HOIPs. Higher n‐value HOIP demonstrate a reduced ferroelectric switching energy barrier, providing valuable insights for optimizing ...
Chuanzhao Li   +6 more
wiley   +1 more source

Ancestral Protein‐Based Lighting

open access: yesAdvanced Materials, EarlyView.
The ancestral sequence reconstruction (ASR) method applied to a large dataset of modern fluorescent proteins (FPs) led to a bright ancestral‐like FP suitable for photon down‐conversion in bio‐hybrid light‐emitting diodes (Bio‐HLEDs). Abstract Protein‐optoelectronics is a paradigm toward eco‐designed and sustainable technologies.
Stephanie Willeit   +7 more
wiley   +1 more source

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