Automation and Active Learning for the Multi‐Objective Optimization of Antibody Formulations
Successful antibody formulation necessitates balancing factors such as thermal stability, colloidal stability, and viscosity across a vast excipient design space. This work integrates robotic liquid handling, high‐throughput biophysical characterization, and multi‐objective Bayesian optimization in an iterative closed‐loop Design‐Build‐Test‐Learn cycle.
D. Christopher Radford +3 more
wiley +1 more source
When success becomes a barrier: tackling inertia in necessary change in clinical practice in neonatal vascular access. [PDF]
van Rens M, Hugill K, Bayoumi MAA.
europepmc +1 more source
A Pan‐Methylome Framework for Population‐Scale Bacterial Epigenomics
A scalable quantitative framework unlocks population‐level comparative epigenomics in bacteria. By transforming site‐level data into standardized traits, this approach reconstructs methylation‐informed phylogenies and defines the core epigenome.
Bin Ma +22 more
wiley +1 more source
Robust Multi-Agent Path Finding Method for Obstacles and Environmental Changes in Factory Environments. [PDF]
Park S +5 more
europepmc +1 more source
Enhanced Ionic Conductivity at the Solid Electrolyte Interphase of Oxygen‐Doped Li6PS5Cl
Machine‐learned molecular dynamics and machine‐learning‐based phase identification reveal the kinetically formed SEI at buried Li | Li6PS5Cl interfaces. The SEI is dominated by Li2S‐based anion‐substituted phases, while oxygen doping enhances SEI ionic conductivity.
Sojeong Yang +6 more
wiley +1 more source
Phylogenetic constraints, conservatism, and convergence shape three-dimensional variation in flower morphology of a tropical orchid radiation. [PDF]
Artuso S +4 more
europepmc +1 more source
An empirical‐aided active learning framework is developed to optimize high‐throughput laser‐induced photothermal annealing of silicon suboxide anodes. By integrating probabilistic machine learning with empirical domain knowledge, this approach achieves optimal electrochemical performance using limited experiments.
Chaeyoung Park +3 more
wiley +1 more source
Invasion Patterns and Niche Dynamics of the Pollinivorous Florida Calligrapher, <i>Toxomerus floralis</i> (Diptera: Syrphidae) in the Afrotropical Region. [PDF]
Muller B +20 more
europepmc +1 more source
Hamaker Constants of van der Waals Materials under Clean‐Interface Conditions
Clean‐interface adhesion in representative van der Waals materials is quantified by Ultra High Vacuum (UHV) Atomic Force Microscopy (AFM) with in situ cleaning and calibrated probes. Benchmark Hamaker constants for graphene, MoS2, and SiO2 are established, while humidity is shown to reversibly amplify adhesion, explaining much of the scatter in ...
Daniel Gallego‐Fuente +3 more
wiley +1 more source
Robust LPV pitch control of autonomous underwater vehicle with input constraints. [PDF]
Zhang H +5 more
europepmc +1 more source

