Heterogeneity manifestation and formation mechanism of school youth sports activity quality: a multi-case comparative study based on the configurational perspective. [PDF]
Liu Y, Yin J.
europepmc +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Validation of the Norwegian Version of the Tool to Measure Parenting Self-Efficacy (TOPSE) Questionnaire in Families With Children and Adolescents With Acquired Brain Injury. [PDF]
Rohrer-Baumgartner N +6 more
europepmc +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Development and preliminary evaluation of a German questionnaire assessing attitudes toward hearing aids and behavioral intention. [PDF]
Mathern C +5 more
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
The Reliability of Repeated Measures of Retrospective Parity and Birth Dates in U.S. Survey Data: A Research Note. [PDF]
Guzzo KB +3 more
europepmc +1 more source
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Performance Optimization of Shield Muck-Based Grouting Materials Using Rice Husk Ash and Micro-Expansive Agents. [PDF]
Fan J, Dai S, Hu F, Liu K, Li K, Zhu J.
europepmc +1 more source

