Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Nurse-led enhanced recovery program for women undergoing elective cesarean section: a quasi-experimental study. [PDF]
Aboushady RM +6 more
europepmc +1 more source
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
Performance Improvement of the Acrylic Acid-Polyvinyl Alcohol Gel Dosimeter with an Organic Additive for Radiation Oncology Applications. [PDF]
Moftah B +4 more
europepmc +1 more source
The causal relationship between Omega-3 fatty acids and Achilles Tendinitis risk: A two-sample Mendelian randomization study in European populations. [PDF]
Wang B +5 more
europepmc +1 more source
Relationships Between Frequency of Attendance, Engagement and Independence in Everyday Activities Among Children and Youth With Intellectual and Other Developmental Disabilities: The Association With Comprehension Difficulties. [PDF]
Axelsson AK, Ivarsson M, Ullenhag A.
europepmc +1 more source
ICIRD: Information-Principled Deep Clustering for Invariant, Redundancy-Reduced and Discriminative Cluster Distributions. [PDF]
Zheng A, Wu RMX, Wang Y, He Y.
europepmc +1 more source
Assessing the national essential medicines list selection processes: Instrument development and testing. [PDF]
Saxena E +3 more
europepmc +1 more source
Exploring causal correlations between oily fish intake and multiple sclerosis: A two-sample Mendelian randomization study. [PDF]
Chang S, Shi K, Zhang M.
europepmc +1 more source

