Results 231 to 240 of about 214,451 (304)

Modeling Mental Health Case-Mix for Quality Improvement-A Comparison of Statistical and AI Models. [PDF]

Healthcare (Basel)
Gao J, Box TL, Liu T, Farmer SL.
europepmc   +1 more source

Chromatin Topology Reconfiguration Orchestrates Thermotolerant Male Fertility via GhAL5 in Cotton

Advanced Science, EarlyView.
This study investigates cotton’s high‐temperature (HT) response using multi‑omics. Dynamic 3D genome changes drive expression bias affecting male fertility. The tolerant line shows controlled chromatin dynamics, while the sensitive line exhibits overactivation.
Yanlong Li, Jing Yang, Weiran Wang, Chunyang Zuo, Liuling Pei, Yizan Ma, Rui Zhang, Yaru Fan, Huanhuan Ma, Yawei Li, Ruizhen Liu, Shuangxia Jin, Longfu Zhu, Jie Kong, Xianlong Zhang, Ling Min   +15 more
wiley   +1 more source

Health workers' perspectives on barriers and opportunities to optimising quality improvement implementation in urban health facilities in Lilongwe, Malawi. [PDF]

BMJ Open Qual
Kumwenda W, Bengtson AM, Wallie S, Villiera JB, Bula AK, Ngoma E, Hosseinipour M, Mwapasa V.   +7 more
europepmc   +1 more source

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

Advanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang, Zibin Li, Yao Xiao, Ji Bian, Caian He, Chao Liu, Lan Gong, Lin Han, Zhigang Liu, Min Wang   +9 more
wiley   +1 more source

Harmonizing Iron Terminology and Nomenclature. [PDF]

Cureus
Nashwan AJ, Zakir B, Hawas Y, Yassin M.
europepmc   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

Advancing the methodology of clinical trials for aging populations: A call to innovation, inclusion, and global relevance. [PDF]

J Nutr Health Aging
Marzetti E, Calvani R, Coelho-Junior HJ.
europepmc   +1 more source

A Community Advisory Board's Role in Disseminating Tai Chi Prime in African American and Latinx Communities: A Pragmatic Application of the Consolidated Framework for Implementation Research. [PDF]

Healthcare (Basel)
Salihu EY, Hallisy K, Malta JS, Joseph DT, Ferrill C, Culotti PC, Juarez RH, Chewning B.   +7 more
europepmc   +1 more source

Career process experiences of male nurse managers: a qualitative research. [PDF]

BMC Nurs
Yöndem Ş, Bilgin O, Köseoğlu N, Alan H, Torun S.   +4 more
europepmc   +1 more source