Results 81 to 90 of about 106,285,319 (279)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Implementation factors and healthcare provider willingness to vaccinate in Latin America and the Caribbean

Journal of Health, Population and Nutrition
Background It is estimated that approximately 80% of childhood cancer cases occur in resource-limited settings and that most unvaccinated children live in middle-income countries.
Maysam R. Homsi, Carol Underwood, Olakunle Alonge, Miguela A. Caniza, Melissa A. Davey-Rothwell   +4 more
doaj   +1 more source

Implementation of a national policy for improving health and social care: a comparative case study using the Consolidated Framework for Implementation Research

BMC Health Services Research, 2019
Background Comprehensive policies are becoming common for addressing wicked problems in health and social care. Success of these policies often varies between target organizations. This variation can often be attributed to contextual factors.
Helena Strehlenert, Johan Hansson, Monica Elisabeth Nyström, Henna Hasson   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A conceptual framework for the implementation of quality management systems [PDF]

, 2014
© 2014 Taylor & Francis. Some evidence suggests that Quality Management Systems (QMSs) make a positive contribution towards the competitiveness of organisations.
Luis, Rocha-Lona, Vikas, Kumar, Jose, Garza-Reyes, Kumar, Vikas, Garza-Reyes, Jose Arturo, Rocha-Lona, Luis   +5 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

The Consolidated Framework for Implementation Research (CFIR): a useful theoretical framework for guiding and evaluating a guideline implementation process in a hospital-based nursing practice [PDF]

, 2015
Background: Implementing clinical practice guidelines (CPGs) in healthcare settings is a complex intervention involving both independent and interdependent components.
Birgit Heckemann, Heckemann, B., Helga E. Breimaier, Halfens, R.J.G., Lohrmann, C., Ruud J. G. Halfens, Christa Lohrmann, Breimaier, H.E.   +7 more
core   +2 more sources

Rapid versus traditional qualitative analysis using the Consolidated Framework for Implementation Research (CFIR)

Implementation Science, 2021
Background Qualitative approaches, alone or in mixed methods, are prominent within implementation science. However, traditional qualitative approaches are resource intensive, which has led to the development of rapid qualitative approaches.
Andrea L. Nevedal, Caitlin M. Reardon, Marilla A. Opra Widerquist, George L. Jackson, Sarah L. Cutrona, Brandolyn S. White, Laura J. Damschroder   +6 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Developing the tools of implementation science in substance use disorders treatment: Applications of the consolidated framework for implementation research. [PDF]

Psychology of Addictive Behaviors, 2011
The implementation of evidence-based treatments (EBTs) and practices (EBPs) depends on both top-down and bottom-up responsibilities. Many articles in this special section on Implementation Science in Substance Use Disorders address the interaction between these two approaches when implementing new substance use disorder (SUD) treatments.
Sorensen, James L, Kosten, Thomas
openaire   +4 more sources