Results 241 to 250 of about 1,463,763 (376)

Surgical treatment of non-unions in the ulna and radius: a one-year outcome study. [PDF]

open access: yesEur J Trauma Emerg Surg
Findeisen S   +9 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Auditory-evoked changes in slow oscillations and spindles correlate with memory consolidation in children with epilepsy and controls. [PDF]

open access: yesClin Neurophysiol
Kwon H   +9 more
europepmc   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

743 | ROLE OF CONSOLIDATION AFTER BRENTUXIMAB VEDOTIN TREATMENT IN RELAPSED/REFRACTORY MYCOSIS FUNGOIDES: POLISH LYMPHOMA RESEARCH GROUP RETROSPECTIVE MULTICENTER STUDY [PDF]

open access: bronze
Ewa Chmielowska   +5 more
openalex   +1 more source

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