Results 161 to 170 of about 2,853,808 (283)

Influence of Southeast China's seawater chemistry on the performance development of cement-sodium silicate grout. [PDF]

Sci Rep
Dai H, Wang L, Wang Q, Li L, Zhou Z, Zhang C, Bai T, Liu H, Gao H, Wang H, Zheng B.   +10 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Lung ultrasound versus chest radiography for the detection of early postoperative pulmonary complications in children undergoing cardiac surgery. [PDF]

Eur J Pediatr
Bakry NA, Mansour MG, Ali HA, Abouelhoda AM, Abdelhamid MI, Ebrahim BA.   +5 more
europepmc   +1 more source

The Graduation Seminar: A Space for the Consolidation of Professional Competencies in the Bachelor's Degree

Revista Tecnológica-Educativa Docentes 2.0 (RTED)
El espacio curricular fortalece la articulación entre teoría y práctica profesional, consolidando competencias clave para una intervención educativa contextualizada y pertinente. La presente investigación tuvo el objetivo de describir experiencias en los seminarios de titulación de la licenciatura en intervención educativa (LIE) de la Universidad ...
openaire   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Electrical impedance tomography as an early bedside alert for mucus plug-related airway obstruction. [PDF]

Lung India
Sharma N, Choudhary R, Dilesh PK, Yadav T.   +3 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Male and Female Mice Show Similar Fear Memory Performance Despite Hippocampal Immediate Early Gene Expression Differences During Encoding and Consolidation. [PDF]

Cells
McDonald KO, Yu T, Prabhu A, Aton SJ.
europepmc   +1 more source

The Undergraduate Degree in International Relations in Spain: From Emergence to Consolidation (2009-2019)

Comillas Journal of International Relations, 2019
The paper aims to analyze the (r)evolution of the undergraduate degree in international relations in Spain during its first decade of existence. After summarizing the difficulties for its implementation in 2009 it overviews the development in terms of student population and universities, with a special focus on the geographical dispersion and the ...
openaire   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source