Results 191 to 200 of about 115,917 (266)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Clinical features and risk factors of plastic bronchitis in Mycoplasma pneumoniae pneumonia children with pulmonary consolidation: a prospective cohort study. [PDF]

Front Pediatr
Yu Y, Wang F, Wang H.
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Feasibility and Acceptability of a Remote Sleep-Dependent Memory Assessment in Older Adults With Cognitive Concerns: Pilot Cross-Sectional Study. [PDF]

JMIR Aging
Tan CCY, Lam A, Ireland D, Bradford D, Cross N, Kurniawan MT, Simonetti S, Fripp J, Naismith SL.   +8 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Association of lung ultrasound findings with disease severity in <i>Mycoplasma pneumoniae</i> pneumonia among the pediatric population. [PDF]

Transl Pediatr
Han MY, Gong SD, Lin JH, Meng GP, Zhao Q, Gao J, Lu YM, Xiao JJ.   +7 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Restoring access to long-term social recognition memories disrupted by sleep deprivation. [PDF]

Sci Adv
Sarma A, Paraciani C, Cao J, Tyumeneva E, Stacchiola C, Meijer EL, de Vries N, Smit S, Meijer F, Bonne M, Billeter JC, Meerlo P, Havekes R.   +12 more
europepmc   +1 more source

Head-to-head comparison of maximum standardized uptake value and three-dimensional consolidation-to-tumor ratio for preoperative prediction of International Association for the Study of Lung Cancer grade 3 in clinical stage IA invasive lung adenocarcinoma. [PDF]

J Thorac Dis
Fumimoto S, Sato K, Katsumata T, Hanaoka N.   +3 more
europepmc   +1 more source

A power-exponential secant modulus model for the compression and settlement behavior of compacted loess fill. [PDF]

Sci Rep
Li Z, Ren S, Shen A, Ni W, Zhong Q.
europepmc   +1 more source