Results 181 to 190 of about 215,037 (402)

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

A comparative study of Chinese ESL learners from Malaysia and the People's Republic of China in their pronunciation of /r/&/l/ [PDF]

open access: yes, 2007
The purpose of this study is to investigate if consonants /r/ presented similar problems for Chinese ESL students from Malaysia and Chinese ESL students from the People’s Republic of China.
Kamarudin, Mohd Fauzi   +2 more
core  

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

open access: yesMolecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina   +17 more
wiley   +1 more source

Study on Error Pattern of Consonant of Children with Functional Dysarthria

open access: yes康复学报, 2015
Objective:To study the distribution characteristics, error pattern and acquistion features of disordered consonants of children with functional dysarthria, so as to provide the theoretical guidance for the design of pronunciation rehabilitation programs ...
Zhihong DU   +4 more
doaj  

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Monolingual and bilingual spanish-catalan speech recognizers developed from SpeechDat databases [PDF]

open access: yes, 2000
Under the SpeechDat specifications, the Spanish member of SpeechDat consortium has recorded a Catalan database that includes one thousand speakers. This communication describes some experimental work that has been carried out using both the Spanish and ...
Mariño Acebal, José Bernardo   +3 more
core  

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

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