Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Demographic and Acoustic Factors related to Automatic Speech Recognition Inaccuracies for Child African American English Speakers. [PDF]
Fletcher BN +8 more
europepmc +1 more source
Measuring consonant identification in nonsense syllables, words, and sentences.
D. Woods, E. Yund, T. Herron
semanticscholar +1 more source
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Order of Consonant Production as a Predictor of Speech Outcomes After Primary Palatoplasty. [PDF]
Hanai U +8 more
europepmc +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Phoneme Manner Types and Function and Content Words as Biomarkers for Different Types of Stutters in Speakers Who Continue to Stutter. [PDF]
Howell P, Au JK, Barrett L.
europepmc +1 more source
Consonant-Vowel-Consonants for Error-Free Code Entry
Nikola K. Blanchard +2 more
openalex +1 more source
DIMINUTION OF HIGH FREQUENCY ENERGY AS A CUE TO THE VOICELESSNESS OF FOLLOWING CONSONANTS [PDF]
Geoffrey Lindsey +2 more
openalex +1 more source

