Results 311 to 320 of about 225,632 (381)

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Resting-State Functional Connectivity Predicts Cochlear-Implant Speech Outcomes. [PDF]

Ear Hear
Esmaelpoor J, Peng T, Jelfs B, Mao D, Shader MJ, McKay CM.   +5 more
europepmc   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Corrigendum: Identifying stuttering in Arabic speakers who stutter: development of a non-word repetition task and preliminary results. [PDF]

Front Pediatr
Alsulaiman R, Harris J, Bamaas S, Howell P.   +3 more
europepmc   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Development of tonality and consonance categorization ability and preferences in 4- to 6-year-old children. [PDF]

Front Psychol
Will JK, Roeske C, Degé F.
europepmc   +1 more source

Comparison of Outcomes After Cochlear Implantation in a Veteran Versus Nonveteran Population. [PDF]

Otol Neurotol Open
Tripathi SH, Adams SM, Wong EM, Petito G, Shapiro S, Grisel J, Breen J, Dhanda Patil R.   +7 more
europepmc   +1 more source

Impact of Japanese L1 Rhythm on English L2 Speech. [PDF]

Lang Speech
Kawase S, Davis C, Kim J.
europepmc   +1 more source

Short-term effects of acoustically controlled auditory training in children with impaired school performance. [PDF]

Codas
Tavoni JR, Santos MFCD.
europepmc   +1 more source

Segmentation window of speech information processing in the human auditory cortex. [PDF]

Sci Rep
Hayashi M, Kida T, Inui K.
europepmc   +1 more source