Results 51 to 60 of about 186,668 (324)

Temporal Variability and Stability in Infant-Directed Sung Speech: Evidence for Language-specific Patterns. [PDF]

open access: yes, 2011
In this paper, sung speech is used as a methodological tool to explore temporal variability in the timing of word-internal consonants and vowels.
Falk, Simone
core   +2 more sources

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Holger Pedersen's "Études lituaniennes" revisited [PDF]

open access: yes, 2010
Holger Pedersen’s "Études lituaniennes" reflects the issues under discussion at the time of its publication (1933). Its five unequal chapters deal with the following topics: I.
Kortlandt, Frederik H. H.
core  

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Analysis of the Word-Initial Segment with Reference to Lemmatising Zulu Nasal Nouns

open access: yesLexikos, 2012
<p>The process of lemmatising nasal nouns in the Zulu lexicon is problematic. The traditional method is to lemmatise a Zulu lexical noun by etymological noun-stem. This practice creates difficulties in harmonising lexical nouns with their syntactic
M.H. Mpungose
doaj   +1 more source

Dichotic spectral integration range for consonant recognition in listeners with normal hearing

open access: yesFrontiers in Psychology, 2022
Dichotic spectral integration range, or DSIR, was measured for consonant recognition with normal-hearing listeners. DSIR is defined as a frequency range needed from 0 to 8,000 Hz band in one ear for consonant recognition when low-frequency information of
Yang-Soo Yoon, Dani Morgan
doaj   +1 more source

Subphonemic and suballophonic consonant variation : the role of the phoneme inventory [PDF]

open access: yes, 2013
Consonants exhibit more variation in their phonetic realization than is typically acknowledged, but that variation is linguistically constrained. Acoustic analysis of both read and spontaneous speech reveals that consonants are not necessarily realized ...
Lavoie, Lisa M.
core  

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