Results 81 to 90 of about 53,620 (288)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
, 2010 Elsewhere I have argued that the Indo-European verbal system can be understood in terms of its Indo-Uralic origins because the reconstructed Indo-European endings can be derived from combinations of Indo-Uralic morphemes by a series of well-motivated ...
Kortlandt, Frederik H. H.
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Towards a model of phonological acquisition in government phonology [PDF]
, 1998 Child phonology shows some interesting and systematic differences from adult phonology. In child phonology, for example, vowel harmony and consonant harmony are common phonological effects (Ingram 1986).
Tolson, Lucy
core
Gendang Melayu Sarawak (GMS) – Sarawak Malay Drum, the Dying and Forgotten Tradition
BioResourcesThis work was conducted using the Picoscope signal extraction procedure, which revealed significant insights regarding the belian wood and its application in Gendang Melayu Sarawak (GMS) production.
Aaliyawani Ezzerin Sinin +4 more
doaj +2 more sources
Pattern of language-related potential maps in cluster and noncluster initial consonants in consonant-vowel (CV) syllables [PDF]
Songklanakarin Journal of Science and Technology (SJST), 2006 Mismatch negativity (MMN) was used to investigate the processing of cluster and noncluster initial consonants in consonant vowel syllables in the human brain.
Naiphinich Kotchabhakdi +2 more
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Ce que révèle l’ordre d’acquisition des classes naturelles à propos des harmonies consonantiques
Lidil, 2015 Consonant harmony is a common phenomenon in child language. Most of the previous studies on this type of harmony consider this phenomenon as unified. However, pattern production variety prompted us to propose the existence of two distinct phenomena that ...
Naomi Yamaguchi +2 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source