Results 231 to 240 of about 25,115 (305)

Speech sound discrimination in background noise across the lifespan: a comparative study in Mongolian gerbils and humans. [PDF]

Front Aging Neurosci
Jüchter C, Chi CJ, Beutelmann R, Klump GM.   +3 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Investigating the Relationship Between Early Speech Milestones and Oral-Motor Development in Infants. [PDF]

Acta Paediatr
Allison KM, Radville KM, Martens A, Manjourides J, Rajput N, Zimmerman E.   +5 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Adding noise can reduce response biases in addition to improving perceptual performance. [PDF]

iScience
Rowe E, van Boxtel JJA.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

The Effectiveness of Ultrasound Visual Biofeedback in Articulation Therapy for Children and Adolescents With Speech Sound Disorders: A Systematic Review and Meta-Analysis. [PDF]

Int J Lang Commun Disord
Yiu OY, Wong WHS, Pokta F, Fong AYT, Tso WWY, Ip P.   +5 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Order of Consonant Production as a Predictor of Speech Outcomes After Primary Palatoplasty. [PDF]

Plast Reconstr Surg Glob Open
Hanai U, Akamatsu T, Okawa T, Kaneko A, Watanabe M, Muramatsu H, Tsunoda Y, Nemoto H, Imagawa K.   +8 more
europepmc   +1 more source

Acoustic parameter combinations underlying mapping of pseudoword sounds to multiple domains of meaning: Representational similarity analyses and machine-learning models. [PDF]

J Acoust Soc Am
Kumar GV, Lacey S, Dorsi J, Nygaard LC, Sathian K.   +4 more
europepmc   +1 more source