Results 111 to 120 of about 1,645,346 (312)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Case Summary: Calypso, Atlantic and Manufacturas del Rio (Nicaragua and El Salvador) [PDF]

, 2006
WRC report on an investigation of labor violations at three factories in Central America owned by the Argus Group.
Worker Rights Consortium
core   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Worker Rights Consortium Remediation Report re Lianglog Socks Co. Ltd (China) [PDF]

, 2009
WRC report on the efforts to remediate violations previously found at Lianglong Socks, a producer of hosiery for RJ McCarthy Ltd, a supplier of school uniforms.
Worker Rights Consortium
core   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Konsorcjum w prawie zamówień publicznych – solidarność czynna i bierna wobec osób trzecich w postępowaniu i na etapie realizacji umowy

Acta Iuris Stetinensis, 2018
The main purpose of the article is an analysis of the consortium in the provisions of the public procurement law in terms of joint and several liability. There are many conceptions of the examined issue which are reflected in various legal acts.
Maciej Stanisław Ratajczak
doaj   +1 more source

Worker Rights Consortium Assessment re Jerzees Choloma (Honduras): Report of Findings and Recommendations [PDF]

, 2007
WRC report on its assessment of labor violations at the Jerzees Choloma factory in Honduras. Includes a description of evidence and assessment logistics, and recommendations for remedial action to be taken by the ...
Worker Rights Consortium
core   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

Crystal Digital PCR™ Enables Precise Quantification of Species Abundance in Microbial Mixtures

Microorganisms
Accurate bacterial quantification is critical in many biological fields, from clinical diagnostics to environmental microbiology. Here, we establish a robust workflow for absolute quantification of bacterial species within mixed communities using Crystal
Louis Delecourt, Mila Reset, Lionel Bertaux, James Sturgis, Yann Denis, Marie-Thérèse Giudici-Orticoni, Magali Roger, Christophe Bordi   +7 more
doaj   +1 more source

ENT COBRA (Consortium for Brachytherapy Data Analysis): interdisciplinary standardized data collection system for head and neck patients treated with interventional radiotherapy (brachytherapy)

Journal of Contemporary Brachytherapy, 2016
Purpose : Aim of the COBRA (Consortium for Brachytherapy Data Analysis) project is to create a multicenter group (consortium) and a web-based system for standardized data collection. Material and methods: GEC-ESTRO (Groupe Européen de Curiethérapie –
Luca Tagliaferri, György Kovács, Rosa Autorino, Ashwini Budrukkar, Jose Luis Guinot, Guido Hildebrand, Bengt Johansson, Rafael Martìnez Monge, Jens E. Meyer, Peter Niehoff, Angeles Rovirosa, Zoltàn Takàcsi-Nagy, Nicola Dinapoli, Vito Lanzotti, Andrea Damiani, Tamer Soror, Vincenzo Valentini   +16 more
doaj   +1 more source