Results 11 to 20 of about 543,244 (313)
Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2C19 Genotype and Clopidogrel Therapy: 2022 Update
Clinical pharmacology and therapy, 2022 CYP2C19 catalyzes the bioactivation of the antiplatelet prodrug clopidogrel, and CYP2C19 genotype impacts clopidogrel active metabolite formation. CYP2C19 intermediate and poor metabolizers who receive clopidogrel experience reduced platelet inhibition ...Craig R. Lee, Jasmine A. Luzum, K. Sangkuhl, Roseann S. Gammal, M. Sabatine, C. Stein, D. Kisor, N. Limdi, Yee Ming Lee, S. Scott, J. Hulot, D. Roden, A. Gaedigk, K. Caudle, T. Klein, Julie A. Johnson, A. Shuldiner +16 moresemanticscholar +1 more sourceApplication of team science best practices to the project management of a large, multi-site lung cancer screening research consortium
Journal of Clinical and Translational Science, 2023 Research is increasingly conducted through multi-institutional consortia, and best practices for establishing multi-site research collaborations must be employed to ensure efficient, effective, and productive translational research teams.Julie S. Steiner, Erica Blum-Barnett, Betsy Rolland, Courtney R. Kraus, Jocelyn V. Wainwright, Ruth Bedoy, Yannica Theda Martinez, Elizabeth R. Alleman, Roxy Eibergen, Lisa E. Pieper, Nikki M. Carroll, Brian Hixon, Andrew Sterrett, Katharine A. Rendle, Chelsea Saia, Anil Vachani, Debra P. Ritzwoller, Andrea Burnett-Hartman +17 moredoaj +1 more sourceThe Liquid Biopsy Consortium: Challenges and opportunities for early cancer detection and monitoring
Cell Reports Medicine, 2023 Summary The emerging field of liquid biopsy stands at the forefront of novel diagnostic strategies for cancer and other diseases. Liquid biopsy allows minimally invasive molecular characterization of cancers for diagnosis, patient stratification to ...S. Batool, A. Yekula, Prerna Khanna, Tiffaney Hsia, Austin S. Gamblin, Emil Ekanayake, Ana K. Escobedo, Dong Gil You, Cesar M. Castro, H. Im, Tuğba Kiliç, Michelle A. Garlin, Johan Skog, D. Dinulescu, Jonathan Dudley, Nishant Agrawal, Jordan Cheng, F. Abtin, Denise R. Aberle, David Chia, D. Elashoff, Tristan Grognan, K. Krysan, Scott S. Oh, Charles Strom, M. Tu, F. Wei, Rena R. Xian, S. Skates, D. Zhang, T. Trinh, Mark Watson, R. Aft, S. Rawal, Ashutosh Agarwal, S. Kesmodel, Changhuei Yang, Cheng Shen, Fred H. Hochberg, D. T. Wong, Abhijit A. Patel, N. Papadopoulos, C. Bettegowda, Richard J. Cote, Sudhir Srivastava, Hakho Lee, Bob S. Carter, L. Balaj +47 moresemanticscholar +1 more sourceThe REDCap Consortium: Building an International Community of Software Platform Partners
Journal of Biomedical Informatics, 2019 The Research Electronic Data Capture (REDCap) data management platform was developed in 2004 to address an institutional need at Vanderbilt University, then shared with a limited number of adopting sites beginning in 2006. Given bi-directional benefit in P. Harris, Robert Taylor, Brenda L. Minor, V. Elliott, Michelle Fernandez, Lindsay O'Neal, Laura McLeod, Giovanni Delacqua, Francesco Delacqua, Jacqueline Kirby, Stephany N. Duda +10 moresemanticscholar +1 more sourceTricuspid Valve Academic Research Consortium Definitions for Tricuspid Regurgitation and Trial Endpoints.
Journal of the American College of Cardiology, 2023 Interest in the pathophysiology, etiology, management, and outcomes of patients with tricuspid regurgitation (TR) has grown in the wake of multiple natural history studies showing progressively worse outcomes associated with increasing TR severity, even ...R. Hahn, Matthew K. Lawlor, Charles J Davidson, V. Badhwar, A. Sannino, Ernest Spitzer, P. Lurz, B. Lindman, Y. Topilsky, S. Baron, S. Chadderdon, Omar Khalique, G. Tang, M. Taramasso, P. Grayburn, L. Badano, J. Leipsic, J. Lindenfeld, Stephan Windecker, S. Vemulapalli, B. Redfors, Maria C. Alu, David J. Cohen, J. Rodés‐Cabau, G. Ailawadi, Michael J. Mack, O. Ben-Yehuda, Martin B Leon, J. Hausleiter, Suzanne A. Arnold, V. Bapat, Natalia Berry, P. Blanke, Daniel Burkhoff, Megan Coylewright, Neal Duggal, Benjamin Z. Galper, Isaac George, Mayra E. Guerrero, N. Hamid, V. Jagadeesan, S. Kodali, Mitchell W. Krucoff, Roberto M Lang, Mahesh V. Madhavan, Vallerie McLaughin, Roxana Mehran, F. Philippon, S. Sethi, M. Simonato, Robert Smith, N. Sodhi, J. Spertus, T. Stocker, G. Stone +54 moresemanticscholar +1 more sourceThe GTEx Consortium atlas of genetic regulatory effects across human tissues
Science, 2019 The Genotype-Tissue Expression (GTEx) project was established to characterize genetic effects on the transcriptome across human tissues and to link these regulatory mechanisms to trait and disease associations.F. Aguet, A. Barbeira, Rodrigo Bonazzola, A. Brown, S. Castel, Brian Jo, S. Kasela, Sarah Kim-Hellmuth, Yanyu Liang, Meritxell Oliva, P. Parsana, Elise D. Flynn, L. Frésard, Eric R Gaamzon, Andrew R. Hamel, Yuan He, F. Hormozdiari, P. Mohammadi, Manuel Muñoz-Aguirre, YoSon Park, A. Saha, Ayellet V Segrć, B. Strober, Xiaoquan Wen, Valentin Wucher, Sayantani Das, D. Garrido-Martín, Nicole R. Gay, R. Handsaker, Paul J. Hoffman, Seva Kashin, Alan M. Kwong, Xiao Li, D. MacArthur, J. Rouhana, M. Stephens, E. Todres, A. Viñuela, Gao Wang, Yuxin Zou, Christopher D. Brown, N. Cox, E. Dermitzakis, B. Engelhardt, G. Getz, R. Guigó, Stephen B. Montgomery, Barbara E. Stranger, H. Im, A. Battle, K. Ardlie, T. Lappalainen +51 moresemanticscholar +1 more sourceDiagnostic Criteria for Temporomandibular Disorders (DC/TMD) for Clinical and Research Applications: Recommendations of the International RDC/TMD Consortium Network and Orofacial Pain Special Interest Group
Journal of Oral and Facial Pain and Headache, 2014 Aims The original Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) Axis I diagnostic algorithms have been demonstrated to be reliable.E. Schiffman, R. Ohrbach, E. Truelove, J. Look, G. Anderson, J. Goulet, T. List, P. Svensson, Y. Gonzalez, F. Lobbezoo, A. Michelotti, S. Brooks, W. Ceusters, M. Drangsholt, D. Ettlin, C. Gaul, Louis J. Goldberg, J. Haythornthwaite, L. Hollender, R. Jensen, M. John, A. De Laat, R. de Leeuw, W. Maixner, Marylee J van der Meulen, G. Murray, D. Nixdorf, S. Palla, A. Petersson, P. Pionchon, Barry Smith, C. Visscher, J. Zakrzewska, S. Dworkin +33 moresemanticscholar +1 more sourceRevision and Update of the Consensus Definitions of Invasive Fungal Disease From the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium
Clinical Infectious Diseases, 2019 Background Invasive fungal diseases (IFDs) remain important causes of morbidity and mortality. The consensus definitions of the Infectious Diseases Group of the European Organization for Research and Treatment of Cancer and the Mycoses Study Group have ...J. Donnelly, S. Chen, C. Kauffman, W. Steinbach, J. Baddley, P. Verweij, C. Clancy, J. Wingard, S. Lockhart, A. Groll, T. Sorrell, M. Bassetti, H. Akan, B. Alexander, D. Andes, É. Azoulay, R. Bialek, R. Bradsher, S. Bretagne, T. Calandra, A. Caliendo, E. Castagnola, M. Cruciani, M. Cuenca‐Estrella, C. Decker, S. Desai, B. Fisher, T. Harrison, C. Heussel, H. E. Jensen, C. Kibbler, D. Kontoyiannis, B. Kullberg, K. Lagrou, F. Lamoth, T. Lehrnbecher, Jurgen Loeffler, O. Lortholary, J. Maertens, O. Marchetti, K. Marr, H. Masur, J. Meis, C. Morrisey, M. Nucci, L. Ostrosky-Zeichner, L. Pagano, T. Patterson, J. Perfect, Z. Ráčil, E. Roilides, M. Ruhnke, Cornelia Schaefer Prokop, S. Shoham, M. Slavin, D. Stevens, G. Thompson, J. Vázquez, C. Viscoli, Thomas J. Walsh, A. Warris, L. Wheat, P. L. White, T. Zaoutis, P. Pappas +64 moresemanticscholar +1 more source