Results 201 to 210 of about 1,617,594 (350)

Correction: Community perspectives on AI/ML and health equity: AIM-AHEAD nationwide stakeholder listening sessions. [PDF]

PLOS Digit Health
Vishwanatha JK, Christian A, Sambamoorthi U, Thompson EL, Stinson K, Syed TA, AIM-AHEAD Consortium.   +6 more
europepmc   +1 more source

Tissue Engineered Human Elastic Cartilage From Primary Auricular Chondrocytes for Ear Reconstruction

Advanced Functional Materials, EarlyView.
Despite over three decades of research, no tissue‐engineered solution for auricular reconstruction in microtia patients has reached clinical translation. The key challenge lies in generating functional elastic cartilage ex vivo. Here, we integrate synergistic cell‐biomaterial strategies to engineer auricular grafts with mechanical and histological ...
Philipp Fisch, Sandra Kessler, Simone Ponta, Anna Puiggalí‐Jou, Guoliang Lyu, Killian Flégeau, Anastasiya Martyts, Florian Roth, David Fercher, Filippo M. Rijli, Daniel Simmen, Eva Novoa Olivares, Thomas Linder, Marcy Zenobi‐Wong   +13 more
wiley   +1 more source

Multi-omics provides functional insights and underscores practical challenges in assessing the composition and performance of a nitrifying microbial consortium. [PDF]

Appl Environ Microbiol
Smith DDN, Subasinghe RM, Kehoe C, Grégoire DS.   +3 more
europepmc   +1 more source

A Sacrificial 3D Printed Vessel‐on‐Chip Demonstrates a Versatile Approach to Model Granulation Tissue

Advanced Healthcare Materials, EarlyView.
A novel method that combines 3D printing and organ‐on‐chip technology enables the creation of hollow channels lined with endothelial cells through a fibroblast‐populated connective tissue matrix. The model supports stable metabolic culture conditions, angiogenic sprouting, and immune cell migration, thereby demonstrating an easy and versatile method to
Jonas Jäger, Phil Berger, Andrew I. Morrison, Hendrik Erfurth, Maria Thon, Eva‐Maria Dehne, Susan Gibbs, Jasper J. Koning   +7 more
wiley   +1 more source

Development and Morphological/Microstructural Characterization of a Novel Synergic Synbiotic Co-Encapsulated <i>Lactobacillus</i> spp. Consortium and Kale Powder. [PDF]

Food Sci Nutr
Villanueva-Castañeda M, Antunez-Mojica M, Tapia-Maruri D, Ramírez OCM, Delgado RD, Barrera-Molina AI.   +5 more
europepmc   +1 more source

Bioengineered Lymphatic Vessels in Synthetic Matrices to Study Breast Cancer Cell Functions

Advanced Healthcare Materials, EarlyView.
Lymphatic vessels are involved in cancer metastasis. To study the interplay between metastasizing cancer cells and lymphatic vessels under highly reproducible conditions, advanced in vitro models are required. In this work, 3D lymphatic networks are formed in biomimetic hydrogels and their interactions with invasive and non‐invasive cancer cell‐lines ...
Rodi Odabasi, Lisa A. Krattiger, Magdalini Kanari, Mira A. Jacobs, Lukas O. Moser, Mark W. Tibbitt, Cornelia Halin, Martin Ehrbar   +7 more
wiley   +1 more source

Characterization of 843 children with Zika-related microcephaly in the first three years of life: An individual participant data meta-analysis of 12 cohorts in the Zika Brazilian Cohorts consortium. [PDF]

PLOS Glob Public Health
Miranda-Filho DB, Ximenes RAA, Ramos Montarroyos U, Rosa Abtibol-Bernardino M, Brickley EB, Turchi Martelli CM, Cunha Rodrigues L, Velho Barreto de Araújo T, Ventura LO, Leal MC, Neves Santos D, Marques Dos Santos L, Monteiro Santos L, Rabelo Gomes M, de Siqueira IC, Serra L, Rios DPMS, Carvalho A, Silva AM, Silva Sousa P, Ribeiro MC, Campos MG, Passos SD, Bertozzi APP, Gazeta RE, Catalan DT, Queiroz Gurgel R, Lopes ASA, Medeiros AMC, Brasil P, Nielsen-Saines K, Vasconcelos Z, Zin AA, Mussi-Pinhata MM, Negrini SFBM, Negrini BVM, Caldas CACT, Vivacqua D, Coelho BP, Peixoto LFAA, Bôtto-Menezes C, Benzecry SG, de Oliveira CS, Paschoal JKSF, Serra EMF, Gomes LTS, Moreira ME, Hofer CB, Zika Brazilian Cohorts Consortium (ZBC Consortium).   +48 more
europepmc   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Accelerating evidence generation to implementation: Establishment of the Leading Awareness to Action through Implementation of Cardiometabolic Efforts (LATTICE) consortium. [PDF]

Am J Prev Cardiol
Jones LK, Gluckman TJ, Bhatt AS, Boer L, Bonaca MP, Campbell-Salome G, Davis E, Desai NR, George J, Head L, Marvel FA, Penn M, Peterson ED, Scirica BM, Shah NP, Wilemon K, Kalich BA, Martin SS.   +17 more
europepmc   +1 more source

Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies

Advanced Healthcare Materials, EarlyView.
Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer, Dolores J. Salander, Witold Szymanski, Johannes Graumann, Yukai Wang, Kai Zhao, Jörg W. Bartsch, María Gómez‐Serrano, Daniel Bachurski, Silke Reinartz, Elke von Pogge von Strandmann   +10 more
wiley   +1 more source