Results 41 to 50 of about 1,519,093 (354)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Unity is strength: creation and future actions for a consortium for HIV cure research in Latin America and the Caribbean ‘Lac-Cura’

open access: yesHIV Research & Clinical Practice
The development of effective HIV cure strategies is crucial. However, most research in this area has been concentrated in high-income countries, underscoring the need to expand efforts to regions like Latin America and the Caribbean (LAC), which face ...
Gabriela Turk   +9 more
doaj   +1 more source

Worker Rights Consortium Assessment re Hugger de Honduras and Vision Tex (Honduras): Findings, Recommendations and Status Report [PDF]

open access: yes, 2009
WRC report on its investigation of the failure of two factories in Honduras to provide compensation to their workers.
Worker Rights Consortium
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Produção de diferentes variedades de mandioca em sistema agroecológico Growth and production of different cassava varieties in an agroeological system

open access: yesRevista Brasileira de Engenharia Agrícola e Ambiental, 2009
Neste trabalho, conduzido na comunidade de Morro Alto, município de Acauã, PI, localizada na Serra da Parreira, situada a 620 m de altitude, objetivou-se avaliar o crescimento e a produção da mandioca em cultivo consorciado com guandu, sorgo, caupi ...
Alineaurea F. Silva   +5 more
doaj   +1 more source

Implementation of Blockchain Consortium to Prioritize Diabetes Patients’ Healthcare in Pandemic Situations

open access: yesIEEE Access, 2021
Diabetes is a metabolic disorder caused by high blood sugar levels, which can harm the kidneys, the heart, the eyes, and blood vessels. During the Covid-19 pandemic, diabetes patients were most affected. In the existing healthcare system, medical data is
Ganesan Subramanian   +1 more
doaj   +1 more source

Case Summary: Teerapat Industries (Thailand) [PDF]

open access: yes, 2008
WRC report on its investigation of labor violations at a Teerapat Industries factory in Thailand following complaints by concerned workers.
Worker Rights Consortium
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Assessment of productive parameters in broilers and supplemented by probiotic microorganisms

open access: yesTemas Agrarios, 2015
Poultry systems intended for the production of broilers usually handle high poultry densities to obtain a higher production rate of meat by confinement area, situation that results in animal stress and thus zootechnical low yields.
Luz A. Gutiérrez   +2 more
doaj   +1 more source

Worker Rights Consortium Assessment re Lianglong Socks Co. Ltd (China): Findings, Recommendations, and Status Report [PDF]

open access: yes, 2008
WRC report of its assessment of labor violations at the Lianglong factory in China.
Worker Rights Consortium
core   +1 more source

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