Results 121 to 130 of about 188,376 (288)
Arthur, roi méhaignié. Une lecture de la première branche du Haut Livre du Graal
Clément Courteau
doaj +1 more source
The role of lipid metabolism in neuronal senescence
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Green industrial policy is an important means to achieve coordinated development of the environment and industry. Enterprises are the primary bodies involved in the green transformation of the market.
Yueqi Wang, Wei Wang
doaj +1 more source
Abstract Part III of the paper completes the synthesis in the description of ‘constancy’ and ‘contrast’: in any experiment they are complementary parts in the perception of the objectively determined whole. From a description of the process of perception a personal constant is defined as the individual value of the relative distance from objective ...
openaire +1 more source
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Algorithm for foggy image enhancement based on the total variational Retinex and gradient domain
Considering the preservation of color constancy and the improvement of contrast ratio of foggy image en-hancement, the foggy image enhancement algorithm based on the total variational Retinex gradient domain method was proposed.
Bing-quan CHEN, Hong-li LIU
doaj +2 more sources
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source

