Results 51 to 60 of about 29,695 (259)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Associations between physical fitness and mental toughness in adolescent competitive ballet dancers

open access: yesAnnals of Human Biology
Background Mental toughness (MT) is a critical psychological construct in competitive sports, yet its relationship with physical fitness (PF) remains underexplored, particularly in adolescent athletes.Aim The main purpose of the study was to examine the ...
Lan Zhou, Lovro Štefan
doaj   +1 more source

Using Eye Tracking to Explore the Guidance and Constancy of Visual Variables in 3D Visualization

open access: yesISPRS International Journal of Geo-Information, 2017
An understanding of guidance, which means guiding attention, and constancy, meaning that an area can be perceived for what it is despite environmental changes, of the visual variables related to three-dimensional (3D) symbols is essential to ensure rapid
Bing Liu, Weihua Dong, Liqiu Meng
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Reinterpreting resistance and resilience in ecology: a dual-coupling framework

open access: yesEcology and Society
The multidimensional nature of ecological stability must be understood across two distinct levels: phenomenon and principle. At the phenomenal level, stability emerges as constancy, encompassing diverse forms of identity.
Guanghua Xu, Guoqing Li
doaj   +1 more source

Chromatic illumination discrimination ability reveals that human colour constancy is optimised for blue daylight illuminations.

open access: yesPLoS ONE, 2014
The phenomenon of colour constancy in human visual perception keeps surface colours constant, despite changes in their reflected light due to changing illumination.
Bradley Pearce   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Home - About - Disclaimer - Privacy