Results 41 to 50 of about 52,231 (263)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Surfaces of Constant Curvature in the Pseudo-Galilean Space

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2012
We develop the local theory of surfaces immersed in the pseudo-Galilean space, a special type of Cayley-Klein spaces. We define principal, Gaussian, and mean curvatures.
Željka Milin Šipuš, Blaženka Divjak
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Surfaces of Revolution with Constant Mean Curvature in Galilean 3-Space

open access: yesMathematics
Revolution surfaces with zero mean curvature in the Galilean 3-space have been extensively studied in the literature. However, revolution surfaces with non-zero constant mean curvature in this geometric setting have not yet been investigated in a ...
İsmet Gölgeleyen   +2 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

p-Branes with $$AdS_{p+1}$$ AdSp+1 vacuum as models of $$R^2$$ R2 gravity

open access: yesEuropean Physical Journal C: Particles and Fields, 2019
Branes with constant mean curvature of their hyper-worldsheets of codimension 1 are treated as the Nambu-Goldstone fields of the broken Poincare symmetry.
A. A. Zheltukhin
doaj   +1 more source

Mean curvature flow for generating discrete surfaces with piecewise constant mean curvatures

open access: yesComputer Aided Geometric Design, 2023
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Kazuki Hayashi   +4 more
openaire   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Closed 3-dimensional hypersurfaces with constant mean curvature and constant scalar curvature

open access: yesDuke Mathematical Journal, 1990
The main geometrical result of the paper is that such a hypersurface with non-negative scalar curvature in a space form is isoparametric, i.e. lies in a family of parallel constant mean curvature hypersurfaces.
de Almeida, Sebastião C.   +1 more
openaire   +3 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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