Results 101 to 110 of about 7,169,794 (272)

A new continuum based non-linear finite element formulation for modeling of dynamic response of deep water riser behavior [PDF]

, 2009
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The principal objective of this investigation is to develop a nonlinear continuum based finite element formulation to examine dynamic response of flexible ...
Hosseini Kordkheili, Seyed Ali
core   +3 more sources

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Effect of Pauses in Cycling on Millihertz Battery Impedance

IEEE Access
Li-ion batteries show history-dependent behavior; their voltage response to a current stimulus depends upon the history of current. Such non-local time responses can be described with fractional calculus and circuit elements. We demonstrate that existing
Marcus T. Wilson, Logan I. Cowie, Michael J. Cree   +2 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Is Unsupervised Dimensionality Reduction Sufficient to Decode the Complexities of Electrochemical Impedance Spectra?

ChemElectroChem
As electrochemical research undergoes rapid technological progression, the acquisition of substantial amounts of electrochemical impedance spectra (EIS) becomes increasingly feasible.
Aleksei Makogon, Frederic Kanoufi, Viacheslav Shkirskiy   +2 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Equivalent circuit for assessing pore size distribution in porous electrodes by EIS

Electrochemistry Communications
The size, geometry and arrangement of pores can significantly affect both the activity of electrocatalysts and the performance of supercapacitors. Electrochemical impedance spectroscopy (EIS) is a powerful, non-invasive diagnostic tool for characterizing
Anna Plis, Piotr Połczyński, Rafał Jurczakowski   +2 more
doaj   +1 more source

Charles B. Moore Family papers, 1832-1917

Letter from Mr. and Mrs. D. C. Constant, describing divisions of Union and Confederate loyalty amongst friends and neighbors and their own story of being refugees.
Constant, Mrs. D. C.
core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source